DBP2/YNL112W Summary

DBP2 BASIC INFORMATION

Standard Name	DBP2
Systematic Name	YNL112W
Feature Type	ORF, Verified
Description	Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated mRNA decay and rRNA processing (1)
Name Description	Dead Box Protein

GO Annotations	All DBP2 GO evidence and references
	View Computational GO annotations for DBP2
Molecular Function
Manually curated	RNA helicase activity (ISS)
Biological Process
Manually curated	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (IPI) rRNA processing (IMP)
Cellular Component
High-throughput	cytoplasm (IDA) mitochondrion (IDA) nucleus (IDA)

Mutant Phenotype	All DBP2 Phenotype details and references
Large-scale survey
null	inviable

Interactions	DBP2 All interactions details and references
	66 total interaction(s) for 58 unique genes/features.
Physical Interactions	Affinity Capture-MS: 38 Affinity Capture-RNA: 2 Biochemical Activity: 1 PCA: 16 Two-hybrid: 4
Genetic Interactions	Phenotypic Enhancement: 1 Phenotypic Suppression: 4

Sequence Information

ChrXIV:413641 to 416283 | |

Last Update

Coordinates: 2005-11-07 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1273	413641..414913	2005-11-07	1996-07-31
Intron	1274..2275	414914..415915	2005-11-07	1996-07-31
CDS	2276..2643	415916..416283	2005-11-07	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000005056

DBP2 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for DBP2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for DBP2]

1)	Bond AT, et al. (2001) Absence of Dbp2p alters both nonsense-mediated mRNA decay and rRNA processing. Mol Cell Biol 21(21):7366-79

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