DBP1/YPL119C Summary

DBP1 BASIC INFORMATION

Standard Name	DBP1
Systematic Name	YPL119C
Alias	LPH8
Feature Type	ORF, Verified
Description	Putative ATP-dependent RNA helicase of the DEAD-box protein family; mutants show reduced stability of the 40S ribosomal subunit scanning through 5' untranslated regions of mRNAs (1, 2)
Name Description	Dead Box Protein

GO Annotations	All DBP1 GO evidence and references
	View Computational GO annotations for DBP1
Molecular Function
Manually curated	RNA helicase activity (ISS)
Biological Process
Manually curated	translational initiation (IMP)
Cellular Component
High-throughput	cytoplasm (IDA)

Mutant Phenotype	All DBP1 Phenotype details and references
Large-scale survey
null	sporulation: normal viable

Interactions	DBP1 All interactions details and references
	26 total interaction(s) for 26 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 PCA: 6 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 4 Phenotypic Enhancement: 10 Phenotypic Suppression: 3

Sequence Information

ChrXVI:326263 to 324410 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1854	326263..324410	1996-07-31	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000006040

DBP1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for DBP1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for DBP1]

1)	Jamieson DJ and Beggs JD (1991) A suppressor of yeast spp81/ded1 mutations encodes a very similar putative ATP-dependent RNA helicase. Mol Microbiol 5(4):805-12
2)	Berthelot K, et al. (2004) Dynamics and processivity of 40S ribosome scanning on mRNA in yeast. Mol Microbiol 51(4):987-1001

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