DAT1/YML113W Summary Help

Standard Name DAT1
Systematic Name YML113W
Feature Type ORF, Verified
Description DNA binding protein that recognizes oligo(dA).oligo(dT) tracts; Arg side chain in its N-terminal pentad Gly-Arg-Lys-Pro-Gly repeat is required for DNA-binding; relocalizes to the cytosol in response to hypoxia; not essential for viability (1, 2, 3)
Name Description DATin
Chromosomal Location
ChrXIII:44045 to 44791 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All DAT1 GO evidence and references
  View Computational GO annotations for DAT1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Large-scale survey
null
overexpression
Resources
26 total interaction(s) for 25 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • Protein-RNA: 1

Genetic Interactions
  • Negative Genetic: 18
  • Positive Genetic: 1
  • Synthetic Growth Defect: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 248
Molecular Weight (Da) 27,067
Isoelectric Point (pI) 10.66
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:44045 to 44791 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..747 44045..44791 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004581
References cited on this page View Complete Literature Guide for DAT1
1) Reardon BJ, et al.  (1993) A peptide motif that recognizes A.T tracts in DNA. Proc Natl Acad Sci U S A 90(23):11327-31
2) Winter E and Varshavsky A  (1989) A DNA binding protein that recognizes oligo(dA).oligo(dT) tracts. EMBO J 8(6):1867-77
3) Ghosh Dastidar R, et al.  (2012) The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation. Cell Biosci 2(1):30