DAL80/YKR034W Summary

DAL80 BASIC INFORMATION

Standard Name	DAL80
Systematic Name	YKR034W
Alias	UGA43 1
Feature Type	ORF, Verified
Description	Negative regulator of genes in multiple nitrogen degradation pathways; expression is regulated by nitrogen levels and by Gln3p; member of the GATA-binding family, forms homodimers and heterodimers with Deh1p (2, 3, 4)
Name Description	Degradation of Allantoin

GO Annotations	All DAL80 GO evidence and references
	View Computational GO annotations for DAL80
Molecular Function
Manually curated	sequence-specific DNA binding (IDA) specific transcriptional repressor activity (IDA, IMP) transcription factor activity (IDA)
High-throughput	sequence-specific DNA binding (IDA)
Biological Process
Manually curated	negative regulation of gene-specific transcription from RNA polymerase II promoter (IMP) negative regulation of nitrogen utilization (IMP)
Cellular Component
Manually curated	nucleus (IDA)

Regulatory Role
Binding motifs	DAL80 Transcription Factor Binding Sites and References
	GATAA

Mutant Phenotype	All DAL80 Phenotype details and references
Classical genetics
null	GZF3 mRNA accumulation: increased pseudohyphal growth: decreased
reduction of function	Dur1,2p activity: increased
Large-scale survey
null	filamentous growth: increased hyperosmotic stress resistance: decreased viable

Interactions	DAL80 All interactions details and references
	30 total interaction(s) for 28 unique genes/features.
Physical Interactions	Two-hybrid: 27
Genetic Interactions	Dosage Rescue: 2 Phenotypic Enhancement: 1

Sequence Information

ChrXI:506540 to 507349 | |

Genetic position: 14 cM

Last Update

Coordinates: 2005-12-15 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..810	506540..507349	2005-12-15	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001742

DAL80 RESOURCES

Click on map for expanded view

SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for DAL80

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for DAL80]

1)	Coornaert D, et al. (1992) The UGA43 negative regulatory gene of Saccharomyces cerevisiae contains both a GATA-1 type zinc finger and a putative leucine zipper. Curr Genet 21(4-5):301-7
2)	Marzluf GA (1997) Genetic regulation of nitrogen metabolism in the fungi. Microbiol Mol Biol Rev 61(1):17-32
3)	Svetlov VV and Cooper TG (1998) The Saccharomyces cerevisiae GATA factors Dal80p and Deh1p can form homo- and heterodimeric complexes. J Bacteriol 180(21):5682-8
4)	Magasanik B and Kaiser CA (2002) Nitrogen regulation in Saccharomyces cerevisiae. Gene 290(1-2):1-18

SGD^tm pages Database Copyright © 1997-2010 The Board of Trustees of Leland Stanford Junior University. Permission to use the information contained in this database was given by the researchers/institutes who contributed or published the information. Users of the database are solely responsible for compliance with any copyright restrictions, including those applying to the author abstracts. Documents from this server are provided "AS-IS" without any warranty, expressed or implied. The SGD project at Stanford University is supported by a Genome Research Resource Grant from the US National Human Genome Research Institute, part of the US National Institutes of Health.