Search results for Locus Summary pages at SGD

Your query, D3, returned 47 hits to the following gene names:

Match Gene Name Systematic Name Alias(es) Position Info Description
AAD3 AAD3 YCR107W

ChrIII:313890 to 314981 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1092 313890..314981

Putative aryl-alcohol dehydrogenase; similar to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role; AAD3 has a paralog, AAD15, that arose from a segmental duplication; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family

ADD37 ADD37 YMR184W

ChrXIII:628189 to 628785 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..597 628189..628785

Protein of unknown function; involved in ER-associated protein degradation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YMR184W is not an essential gene; protein abundance increases in response to DNA replication stress

ALD3 ALD3 YMR169C aldehyde dehydrogenase (NAD(+)) ALD3

ChrXIII:600872 to 599352 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1521 600872..599352

Cytoplasmic aldehyde dehydrogenase; involved in beta-alanine synthesis; uses NAD+ as the preferred coenzyme; very similar to Ald2p; expression is induced by stress and repressed by glucose

AMD3 AMD1 YML035C AMD3, AMP deaminase

ChrXIII:208860 to 206428 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2433 208860..206428

AMP deaminase; tetrameric enzyme that catalyzes the deamination of AMP to form IMP and ammonia; thought to be involved in regulation of intracellular purine (adenine, guanine, and inosine) nucleotide pools

BUD3 BUD3 YCL014W YCL012W

ChrIII:96281 to 101191 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..4911 96281..101191

Genetic position: -9 cM

Protein involved in bud-site selection; required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding

BUD30 BUD30 YDL151C

ChrIV:183899 to 183318 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..582 183899..183318

Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; 96% of ORF overlaps the verified gene RPC53; diploid mutant displays a weak budding pattern phenotype in a systematic assay

BUD31 BUD31 YCR063W CWC14

ChrIII:228318 to 228791 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..474 228318..228791

Component of the SF3b subcomplex of the U2 snRNP; increases efficiency of first and second step pre-mRNA splicing; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern; facilitates passage through G1/S Start, but is not required for G2/M transition or exit from mitosis

BUD32 BUD32 YGR262C LDB14, serine/threonine protein kinase BUD32

ChrVII:1017759 to 1016974 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..786 1017759..1016974

Protein kinase; component of the EKC/KEOPS complex with Kae1p, Cgi121p, Pcc1p, and Gon7p; Pyrococcus Bud32 ortholog functions as a P-loop ATPase rather than a protein kinase in the context of the complex; EKC/KEOPS complex is required for t6A tRNA modification and telomeric TG1-3 recombination; may have role in transcription

COD3 COG1 YGL223C COD3, LDB11, SEC36

ChrVII:80365 to 79112 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1254 80365..79112

Essential component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments

CSD3 CHS6 YJL099W CSD3

ChrX:239414 to 241654 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2241 239414..241654

Member of the ChAPs (Chs5p-Arf1p-binding proteins) family; part of the exomer complex that mediates export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; primary component of the Chs5/6 complex that binds directly to membranes; CHS6 has a paralog, BCH2, that arose from the whole genome duplication

DAD3 DAD3 YBR233W-A

ChrII:684977 to 685261 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..285 684977..685261

Essential subunit of the Dam1 complex (aka DASH complex); complex couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis

DID3 VPS24 YKL041W DID3, VPL26, ESCRT-III subunit protein VPS24

ChrXI:360143 to 360817 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..675 360143..360817

One of four subunits of the ESCRT-III complex; forms an endosomal sorting complex required for transport III (ESCRT-III) subcomplex with Did4p; involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway

DLD3 DLD3 YEL071W

ChrV:16355 to 17845 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1491 16355..17845

D-lactate dehydrogenase; part of the retrograde regulon which consists of genes whose expression is stimulated by damage to mitochondria and reduced in cells grown with glutamate as the sole nitrogen source, located in the cytoplasm

EHD3 EHD3 YDR036C MRP5

ChrIV:524713 to 523211 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1503 524713..523211

3-hydroxyisobutyryl-CoA hydrolase; member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis

END3 END3 YNL084C

ChrXIV:471102 to 470053 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1050 471102..470053

EH domain-containing protein involved in endocytosis; actin cytoskeletal organization and cell wall morphogenesis; forms a complex with Sla1p and Pan1p

GID3 UBC8 YEL012W GID3, E2 ubiquitin-conjugating protein UBC8

ChrV:131772 to 132551 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..5 131772..131776
Intron 6..128 131777..131899
CDS 129..780 131900..132551

Ubiquitin-conjugating enzyme that regulates gluconeogenesis; negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro

GLD3 TDH1 YJL052W GLD3, GAPDH, glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1

ChrX:338271 to 339269 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..999 338271..339269

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1; involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell wall; protein abundance increases in response to DNA replication stress; GAPDH-derived antimicrobial peptides secreted by S. cerevisiae are active against a wide variety of wine-related yeasts and bateria

GPD3 GPD2 YOL059W GPD3, glycerol-3-phosphate dehydrogenase (NAD(+)) GPD2

ChrXV:217126 to 218448 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1323 217126..218448

NAD-dependent glycerol 3-phosphate dehydrogenase; expression is controlled by an oxygen-independent signaling pathway required to regulate metabolism under anoxic conditions; located in cytosol and mitochondria; constitutively active but is inactivated via phosphorylation by energy-stress responsive kinase SNF1; GPD2 has a paralog, GPD1, that arose from the whole genome duplication

HMD3 STE5 YDR103W HMD3, NUL3

ChrIV:658350 to 661103 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2754 658350..661103

Genetic position: 63 cM

Pheromone-responsive MAPK scaffold protein; couples activation of the G-protein-coupled pheromone receptor to MAPK activation; intramolecular interaction of PH and VWA domains blocks activation of assembled signaling cascade components (Ste11p, Ste7p and Fus3p) under basal conditions; Gbeta-gamma (Ste4p-Ste18p)-dependent docking at the plasma membrane and binding of PI(4,5)P2 by the PH domain relieves autoinhibition, resulting in pheromone-dependent pathway activation

HRD3 HRD3 YLR207W ubiquitin ligase complex subunit HRD3

ChrXII:556788 to 559289 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2502 556788..559289

ER membrane protein that plays a central role in ERAD; forms HRD complex with Hrd1p and ER-associated protein degradation (ERAD) determinants that engages in lumen to cytosol communication and coordination of ERAD events

IMD3 IMD3 YLR432W IMP dehydrogenase IMD3

ChrXII:1002557 to 1004128 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1572 1002557..1004128

Inosine monophosphate dehydrogenase; catalyzes the rate-limiting step in the de novo synthesis of GTP; member of a four-gene family in S. cerevisiae, constitutively expressed; IMD3 has a paralog, IMD4, that arose from the whole genome duplication

MAD3 MAD3 YJL013C

ChrX:411040 to 409493 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1548 411040..409493

Subunit of spindle-assembly checkpoint complex; involved in delaying anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover; MAD3 has a paralog, BUB1, that arose from the whole genome duplication

MED3 PGD1 YGL025C HRS1, MED3

ChrVII:449957 to 448764 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1194 449957..448764

Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for basal and activated transcription; direct target of Cyc8p-Tup1p transcriptional corepressor

MED31 SOH1 YGL127C MED31

ChrVII:270775 to 270392 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..384 270775..270392

Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; involved in telomere maintenance; conserved with other metazoan MED31 subunits

NMD3 NMD3 YHR170W SRC5, ribosome-binding protein NMD3

ChrVIII:443828 to 445384 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1557 443828..445384

Protein involved in nuclear export of the large ribosomal subunit; acts as a Crm1p-dependent adapter protein for export of nascent ribosomal subunits through the nuclear pore complex

PFD3 PAC10 YGR078C GIM2, PFD3, RKS2

ChrVII:640371 to 639772 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..600 640371..639772

Part of the heteromeric co-chaperone GimC/prefoldin complex; complex promotes efficient protein folding

RAD3 RAD3 YER171W REM1, TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit RAD3

ChrV:527082 to 529418 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2337 527082..529418

Genetic position: 146 cM

5' to 3' DNA helicase; involved in nucleotide excision repair and transcription; subunit of RNA polII initiation factor TFIIH and of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPD protein; mutant has aneuploidy tolerance; protein abundance increases in response to DNA replication stress

RAD30 RAD30 YDR419W DBH1

ChrIV:1303174 to 1305072 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1899 1303174..1305072

DNA polymerase eta; involved in translesion synthesis during post-replication repair; catalyzes the synthesis of DNA opposite cyclobutane pyrimidine dimers and other lesions; involved in formation of post-replicative damage-induced genome-wide cohesion; may also have a role in protection against mitochondrial mutagenesis; mutations in human pol eta are responsible for XPV

RAD33 RAD33 YML011C

ChrXIII:247428 to 246895 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..534 247428..246895

Protein involved in nucleotide excision repair; green fluorescent protein (GFP)-fusion protein localizes to the nucleus

RAD34 RAD34 YDR314C

ChrIV:1092511 to 1090433 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2079 1092511..1090433

Protein involved in nucleotide excision repair (NER); homologous to RAD4

RPD3 RPD3 YNL330C REC3, SDI2, SDS6, MOF6

ChrXIV:19302 to 18001 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1302 19302..18001

Genetic position: -237 cM

Histone deacetylase, component of both the Rpd3S and Rpd3L complexes; regulates transcription, silencing, autophagy and other processes by influencing chromatin remodeling; forms at least two different complexes which have distinct functions and members; Rpd3(L) recruitment to the subtelomeric region is regulated by interaction with the arginine methyltransferase, Hmt1p

Rpd3L histone deacetylase complex subunit DEP1 DEP1 YAL013W FUN54, Rpd3L histone deacetylase complex subunit DEP1

ChrI:129270 to 130487 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1218 129270..130487

Genetic position: 12 cM

Component of the Rpd3L histone deacetylase complex; required for diauxic shift-induced histone H2B deposition onto rDNA genes; transcriptional modulator involved in regulation of structural phospholipid biosynthesis genes and metabolically unrelated genes, as well as maintenance of telomeres, mating efficiency, and sporulation

RUD3 RUD3 YOR216C GRP1

ChrXV:748979 to 747525 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1455 748979..747525

Golgi matrix protein; involved in the structural organization of the cis-Golgi; interacts genetically with COG3 and USO1

SAD3
RAD31
MEC1 YBR136W ESR1, SAD3, RAD31, protein kinase MEC1

ChrII:505668 to 512774 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..7107 505668..512774

Genome integrity checkpoint protein and PI kinase superfamily member; Mec1p and Dun1p function in same pathway to regulate dNTP pools and telomere length; signal transducer required for cell cycle arrest and transcriptional responses to damaged or unreplicated DNA; facilitates replication fork progression and regulates P-body formation under replication stress; promotes interhomolog recombination by phosphorylating Hop1p; associates with shortened, dysfunctional telomeres

SCD3 BMH2 YDR099W SCD3, 14-3-3 family protein BMH2

ChrIV:653607 to 654428 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
5' UTR intron -826..-84 652781..653523
CDS 1..822 653607..654428

Genetic position: 63 cM

14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; BMH2 has a paralog, BMH1, that arose from the whole genome duplication

SED3 DPM1 YPR183W SED3, dolichyl-phosphate beta-D-mannosyltransferase

ChrXVI:900755 to 901558 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..804 900755..901558

Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane; catalyzes the formation of Dol-P-Man from Dol-P and GDP-Man; required for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and protein glycosylation

SLD3 SLD3 YGL113W

ChrVII:295932 to 297938 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2007 295932..297938

Protein involved in the initiation of DNA replication; required for proper assembly of replication proteins at the origins of replication; interacts with Cdc45p; localizes to nuclear foci that become diffuse upon DNA replication stress

SMD3 SMD3 YLR147C SLT16, Sm D3

ChrXII:434463 to 434158 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..306 434463..434158

Core Sm protein Sm D3; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D3

SWD3 SWD3 YBR175W CPS30, SAF35

ChrII:582408 to 583355 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..948 582408..583355

Essential subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5

TAD3 TAD3 YLR316C

ChrXII:766358 to 765266 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..109 766358..766250
Intron 110..177 766249..766182
CDS 178..229 766181..766130
Intron 230..285 766129..766074
CDS 286..1093 766073..765266

Subunit of tRNA-specific adenosine-34 deaminase; forms a heterodimer with Tad2p that converts adenosine to inosine at the wobble position of several tRNAs

TID3 NDC80 YIL144W HEC1, TID3

ChrIX:78074 to 80149 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2076 78074..80149

Component of the kinetochore-associated Ndc80 complex; conserved coiled-coil protein involved in chromosome segregation, spindle checkpoint activity, and kinetochore assembly and clustering; evolutionarily conserved; other members include Ndc80p, Nuf2p, Scp24p, and Spc25p; modified by sumoylation

TPD3 TPD3 YAL016W FUN32, protein phosphatase 2A structural subunit TPD3

ChrI:124879 to 126786 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..1908 124879..126786

Genetic position: .5 cM

Regulatory subunit A of the heterotrimeric PP2A complex; the heterotrimeric protein phosphatase 2A (PP2A) complex also contains regulatory subunit Cdc55p and either catalytic subunit Pph21p or Pph22p; required for cell morphogenesis and transcription by RNA polymerase III

tQ(UUG)D3 tQ(UUG)D3

ChrIV:802802 to 802731 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
Noncoding exon 1..72 802802..802731

Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p

tS(AGA)D3 tS(AGA)D3

ChrIV:1305630 to 1305712 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
Noncoding exon 1..83 1305630..1305712

Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE analysis

UFD3 DOA1 YKL213C UFD3, ZZZ4

ChrXI:34107 to 31960 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2148 34107..31960

WD repeat protein required for ubiquitin-mediated protein degradation; forms a complex with Cdc48p; plays a role in controlling cellular ubiquitin concentration; also promotes efficient NHEJ in postdiauxic/stationary phase; facilitates N-terminus-dependent proteolysis of centromeric histone H3 (Cse4p) for faithful chromosome segregation; protein increases in abundance and relocalizes from nucleus to nuclear periphery upon DNA replication stress

VID30 VID30 YGL227W GID1, glucose-induced degradation complex subunit VID30

ChrVII:69671 to 72547 | ORF Map | GBrowse

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2877 69671..72547

Central component of GID Complex, involved in FBPase degradation; interacts strongly with Gid8p to serve as a scaffold for other GID Complex subunits; contains SPRY domain and 3 domains that are also found in Gid8p - LisH, CTLH, and CRA; required for association of Vid vesicles and actin patches in vacuole import and degradation pathway; shifts the balance of nitrogen metabolism toward glutamate production; localizes to the nucleus and the cytoplasm

VID31 DEF1 YKL054C VID31

ChrXI:338753 to 336537 | ORF Map | GBrowse

Note: this feature is encoded on the Crick strand.

Relative
Coordinates
Chromosomal
Coordinates
CDS 1..2217 338753..336537

RNAPII degradation factor; forms a complex with Rad26p in chromatin, enables ubiquitination and proteolysis of RNAPII present in an elongation complex; mutant is deficient in Zip1p loading onto chromosomes during meiosis