Standard Name	CYT2
Systematic Name	YKL087C
Feature Type	ORF, Verified
Description	Cytochrome c1 heme lyase, involved in maturation of cytochrome c1, which is a subunit of the mitochondrial ubiquinol-cytochrome-c reductase; links heme covalently to apocytochrome c1 (1)
Gene Product Alias	CC1HL 2 , cytochrome c1 heme lyase 1

Chromosomal Location	ChrXI:277863 to 277189 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for CYT2
Molecular Function
Manually curated	holocytochrome-c synthase activity (IMP, ISS)
Biological Process
Manually curated	cytochrome c-heme linkage (IMP, ISS)
Cellular Component
Manually curated	mitochondrial intermembrane space (IDA)
High-throughput	mitochondrion (IDA)

Classical genetics
null	chronological lifespan: decreased
Large-scale survey
null	glycogen accumulation: decreased competitive fitness: decreased dessication resistance: decreased resistance to ethanol: decreased resistance to propolis extract: decreased resistance to quinine: decreased resistance to elesclomol-Cu: decreased resistance to nickel sulfate: decreased respiratory growth: decreased rate respiratory growth: absent sporulation efficiency: decreased utilization of carbon source: decreased vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	65 total interaction(s) for 64 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Affinity Capture-RNA: 3
Genetic Interactions	Dosage Growth Defect: 1 Negative Genetic: 50 Phenotypic Enhancement: 1 Positive Genetic: 3 Synthetic Growth Defect: 2 Synthetic Lethality: 1 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXI:277863 to 277189 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..675 277863..277189 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001570