CPR5/YDR304C Summary Help

CPR5 BASIC INFORMATION

Standard Name CPR5
Systematic Name YDR304C
Alias CYP5
Feature Type ORF, Verified
Description Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the endoplasmic reticulum, catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; transcriptionally induced in response to unfolded proteins in the ER (1, 2)
Name Description Cyclosporin-sensitive Proline Rotamase
GO Annotations All CPR5 GO evidence and references
    View Computational GO annotations for CPR5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All CPR5 Phenotype details and references
Classical genetics
null
Large-scale survey
null
overexpression
Interactions CPR5 All interactions details and references
20 total interaction(s) for 17 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 10
  • Affinity Capture-RNA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Phenotypic Enhancement: 5
  • Phenotypic Suppression: 3

Sequence Information
ChrIV:1072554 to 1071877 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2008-06-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..678 1072554..1071877 2008-06-05 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002712

CPR5 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Localization Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CPR5]

1) Dolinski K, et al.  (1997) All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 94(24):13093-8
2) Frigerio G and Pelham HR  (1993) A Saccharomyces cerevisiae cyclophilin resident in the endoplasmic reticulum. J Mol Biol 233(1):183-8