CPR2/YHR057C Summary Help

CPR2 BASIC INFORMATION

Standard Name CPR2
Systematic Name YHR057C
Alias CYP2
Feature Type ORF, Verified
Description Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway (1, 2, 3)
Name Description Cyclosporin-sensitive Proline Rotamase
GO Annotations All CPR2 GO evidence and references
    View Computational GO annotations for CPR2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All CPR2 Phenotype details and references
Classical genetics
null
Large-scale survey
null
overexpression
Interactions CPR2 All interactions details and references
4 total interaction(s) for 3 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Two-hybrid: 3

Sequence Information
ChrVIII:218845 to 218228 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..618 218845..218228 2005-11-07 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001099

CPR2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Localization Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CPR2]

1) Sykes K, et al.  (1993) Proline isomerases function during heat shock. Proc Natl Acad Sci U S A 90(12):5853-7
2) Dolinski K, et al.  (1997) All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 94(24):13093-8
3) Koser PL, et al.  (1991) The CYP2 gene of Saccharomyces cerevisiae encodes a cyclosporin A-sensitive peptidyl-prolyl cis-trans isomerase with an N-terminal signal sequence. Gene 108(1):73-80