CWP2/YKL096W-A Summary Help

Standard Name CWP2 1
Systematic Name YKL096W-A
Alias LPR1 , YKL097W-A
Feature Type ORF, Verified
Description Covalently linked cell wall mannoprotein; major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored (1, 2, 3)
Name Description Cell Wall Protein 1
Chromosomal Location
ChrXI:259253 to 259531 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All CWP2 GO evidence and references
  View Computational GO annotations for CWP2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 24 genes
Resources
Classical genetics
null
unspecified
Large-scale survey
null
overexpression
unspecified
Resources
30 total interaction(s) for 25 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 5
  • Affinity Capture-Western: 3
  • Biochemical Activity: 1
  • Co-purification: 1
  • PCA: 2
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 8
  • Phenotypic Enhancement: 2
  • Positive Genetic: 3
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 92
Molecular Weight (Da) 8,911
Isoelectric Point (pI) 3.68
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:259253 to 259531 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..279 259253..259531 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001956
References cited on this page View Complete Literature Guide for CWP2
1) van der Vaart JM, et al.  (1995) Identification of three mannoproteins in the cell wall of Saccharomyces cerevisiae. J Bacteriol 177(11):3104-10
2) Skrzypek M, et al.  (1997) Suppressor gene analysis reveals an essential role for sphingolipids in transport of glycosylphosphatidylinositol-anchored proteins in Saccharomyces cerevisiae. J Bacteriol 179(5):1513-20
3) Frieman MB and Cormack BP  (2003) The omega-site sequence of glycosylphosphatidylinositol-anchored proteins in Saccharomyces cerevisiae can determine distribution between the membrane and the cell wall. Mol Microbiol 50(3):883-96