CWP1/YKL096W Summary Help

Standard Name CWP1 1
Systematic Name YKL096W
Alias YJU1 2
Feature Type ORF, Verified
Description Cell wall mannoprotein that localizes to birth scars of daughter cells; linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; required for propionic acid resistance (1, 3, 4, 5, 6)
Name Description Cell Wall Protein 1
Chromosomal Location
ChrXI:261132 to 261851 | ORF Map | GBrowse
Gene Ontology Annotations All CWP1 GO evidence and references
  View Computational GO annotations for CWP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 49 genes
Classical genetics
Large-scale survey
12 total interaction(s) for 8 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • PCA: 3

Genetic Interactions
  • Dosage Rescue: 1
  • Phenotypic Enhancement: 2
  • Phenotypic Suppression: 2
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Expression Summary
Length (a.a.) 239
Molecular Weight (Da) 24,268
Isoelectric Point (pI) 4.32
Phosphorylation PhosphoGRID | PhosphoPep Database
sequence information
ChrXI:261132 to 261851 | ORF Map | GBrowse
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Most Recent Updates
Coordinates Sequence
CDS 1..720 261132..261851 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001579
References cited on this page View Complete Literature Guide for CWP1
1) van der Vaart JM, et al.  (1995) Identification of three mannoproteins in the cell wall of Saccharomyces cerevisiae. J Bacteriol 177(11):3104-10
2) Forrova H, et al.  (1992) Sequence of the novel essential gene YJU2 and two flanking reading frames located within a 3.2 kb EcoRI fragment from chromosome X of Saccharomyces cerevisiae. Yeast 8(5):419-22
3) Kapteyn JC, et al.  (1996) Retention of Saccharomyces cerevisiae cell wall proteins through a phosphodiester-linked beta-1,3-/beta-1,6-glucan heteropolymer. Glycobiology 6(3):337-45
4) Kapteyn JC, et al.  (1999) The contribution of cell wall proteins to the organization of the yeast cell wall. Biochim Biophys Acta 1426(2):373-83
5) Smits GJ, et al.  (2006) Role of cell cycle-regulated expression in the localized incorporation of cell wall proteins in yeast. Mol Biol Cell 17(7):3267-80
6) Mira NP, et al.  (2009) The RIM101 pathway has a role in Saccharomyces cerevisiae adaptive response and resistance to propionic acid and other weak acids. FEMS Yeast Res 9(2):202-16