Standard Name	CTF13 1
Systematic Name	YMR094W
Feature Type	ORF, Verified
Description	Subunit of the CBF3 complex, which binds to the CDE III element of centromeres, bending the DNA upon binding, and may be involved in sister chromatid cohesion during mitosis (2) Also known as: CBF3C
Name Description	Chromosome Transmission Fidelity 1

Chromosomal Location	ChrXIII:455825 to 457261 | ORF Map | GBrowse

	View Computational GO annotations for CTF13
Molecular Function
Manually curated	centromeric DNA binding (TAS) DNA binding, bending (IDA)
Biological Process
Manually curated	kinetochore assembly (IDA) septin ring assembly (IMP)
Cellular Component
Manually curated	CBF3 complex (IDA) condensed nuclear chromosome kinetochore (TAS)

Classical genetics
conditional	colony sectoring: increased heat sensitivity: increased
overexpression	resistance to methylmercury chloride: normal
Large-scale survey
null	haploinsufficient inviable
reduction of function	competitive fitness: decreased
repressible	cell cycle progression in G1 phase: abnormal
Resources	PROPHECY | PhenoM | SCMD | ScreenTroll | Yeast Fitness Database

	72 total interaction(s) for 39 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 1 Affinity Capture-Western: 9 Co-crystal Structure: 1 Co-purification: 1 Reconstituted Complex: 14 Two-hybrid: 6
Genetic Interactions	Dosage Lethality: 13 Dosage Rescue: 3 Synthetic Growth Defect: 8 Synthetic Lethality: 7 Synthetic Rescue: 4
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:455825 to 457261 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1437 455825..457261 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004700