CST26/YBR042C Summary Help

Standard Name CST26 1
Systematic Name YBR042C
Alias PSI1 2
Feature Type ORF, Verified
Description Putative transferase involved in phospholipid biosynthesis; required for incorporation of stearic acid into phosphatidylinositol; affects chromosome stability when overexpressed; CST26 has a paralog, YDR018C, that arose from the whole genome duplication (1, 2, 3)
Name Description Chromosome STability 1
Chromosomal Location
ChrII:321609 to 320416 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All CST26 GO evidence and references
  View Computational GO annotations for CST26
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 55 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
53 total interaction(s) for 46 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 7
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 4
  • Reconstituted Complex: 1
  • Two-hybrid: 3

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 23
  • Positive Genetic: 8
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 397
Molecular Weight (Da) 45,515
Isoelectric Point (pI) 10.15
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:321609 to 320416 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2004-07-16 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1194 321609..320416 2004-07-16 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000246
References cited on this page View Complete Literature Guide for CST26
1) Ouspenski II, et al.  (1999) New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability. Nucleic Acids Res 27(15):3001-8
2) Le Guedard M, et al.  (2009) PSI1 is responsible for the stearic acid enrichment that is characteristic of phosphatidylinositol in yeast. FEBS J 276(21):6412-24
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61