Standard Name	CSM2 1
Systematic Name	YIL132C
Feature Type	ORF, Verified
Description	Component of the Shu complex, which promotes error-free DNA repair; Shu complex mediates inhibition of Srs2p function; structural analysis reveals a similar DNA-binding region in both Psy3p and Csm2p and that both regions work together to form a single DNA binding site; required for accurate chromosome segregation during meiosis (1, 2, 3, 4, 5)
Name Description	Chromosome Segregation in Meiosis 1

Chromosomal Location	ChrIX:100501 to 99860 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for CSM2
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	error-free translesion synthesis (IC) maintenance of rDNA (IGI) meiotic chromosome segregation (IMP) recombinational repair (IGI)
Cellular Component
Manually curated	Shu complex (IPI)
High-throughput	cytoplasm (IDA) nucleus (IDA)

Classical genetics
null	chromosome/plasmid maintenance: abnormal mutation frequency: increased resistance to methyl methanesulfonate: decreased
Large-scale survey
null	anaerobic growth: decreased competitive fitness: decreased haploinsufficient hyperosmotic stress resistance: decreased meiosis: abnormal resistance to methyl methanesulfonate: decreased resistance to cycloheximide: decreased spore germination: decreased starvation resistance: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	63 total interaction(s) for 43 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 Co-crystal Structure: 2 Co-purification: 1 Reconstituted Complex: 1 Two-hybrid: 11
Genetic Interactions	Negative Genetic: 31 Phenotypic Suppression: 1 Positive Genetic: 5 Synthetic Growth Defect: 6 Synthetic Rescue: 4
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIX:100501 to 99860 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 1994-12-10 | Sequence: 1994-12-10
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..642 100501..99860 1994-12-10 1994-12-10
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001394