CSM1/YCR086W Summary Help

CSM1 BASIC INFORMATION

Standard Name CSM1 1
Systematic Name YCR086W
Feature Type ORF, Verified
Description Nucleolar protein that forms a complex with Lrs4p and then Mam1p at kinetochores during meiosis I to mediate accurate homolog segregation; required for condensin recruitment to the replication fork barrier site and rDNA repeat segregation (2, 3, 4)
Name Description Chromosome Segregation in Meiosis 1
GO Annotations All CSM1 GO evidence and references
    View Computational GO annotations for CSM1
Molecular Function
Manually curated
Biological Process
Manually curated
High-throughput
Cellular Component
Manually curated
Mutant Phenotype All CSM1 Phenotype details and references
Classical genetics
null
unspecified
Large-scale survey
null
Interactions CSM1 All interactions details and references
236 total interaction(s) for 156 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 26
  • Affinity Capture-Western: 6
  • Co-localization: 1
  • Two-hybrid: 61
Genetic Interactions
  • Phenotypic Enhancement: 21
  • Phenotypic Suppression: 6
  • Synthetic Growth Defect: 79
  • Synthetic Lethality: 35
  • Synthetic Rescue: 1
Sequence Information
ChrIII:263389 to 263961 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2006-01-12 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..573 263389..263961 2006-01-12 1997-01-28
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000682

CSM1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for CSM1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CSM1]

1) Rabitsch KP, et al.  (2001) A screen for genes required for meiosis and spore formation based on whole-genome expression. Curr Biol 11(13):1001-9
2) Rabitsch KP, et al.  (2003) Kinetochore recruitment of two nucleolar proteins is required for homolog segregation in meiosis I. Dev Cell 4(4):535-48
3) Askree SH, et al.  (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63
4) Johzuka K and Horiuchi T  (2009) The cis element and factors required for condensin recruitment to chromosomes. Mol Cell 34(1):26-35