Standard Name	CPT1
Systematic Name	YNL130C
Feature Type	ORF, Verified
Description	Cholinephosphotransferase; required for phosphatidylcholine biosynthesis and for inositol-dependent regulation of EPT1 transcription; CPT1 has a paralog, EPT1, that arose from the whole genome duplication (1, 2, 3)
Name Description	CholinePhosphoTransferase 2

Chromosomal Location	ChrXIV:380831 to 379558 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for CPT1
Molecular Function
Manually curated	diacylglycerol cholinephosphotransferase activity (IDA, IMP)
Biological Process
Manually curated	CDP-choline pathway (IDA, IMP)
Cellular Component
Manually curated	Golgi apparatus (IDA) mitochondrial outer membrane (IDA)
High-throughput	integral to membrane (ISM)

Pathways	phosphatidic acid and phospholipid biosynthesis phospholipid biosynthesis (Kennedy pathway) superpathway of phospholipid biosynthesis triglyceride biosynthesis

Classical genetics
null	resistance to choline analog G25: increased viable
Large-scale survey
null	competitive fitness: increased haploproficient resistance to benzo[a]pyrene: decreased resistance to dimethyl sulfoxide: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	60 total interaction(s) for 55 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 PCA: 22
Genetic Interactions	Negative Genetic: 27 Positive Genetic: 8 Synthetic Lethality: 1 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIV:380831 to 379558 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 2004-02-03
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..50 380831..380782 2011-02-03 2004-02-03 Intron 51..142 380781..380690 2011-02-03 2004-02-03 CDS 143..1274 380689..379558 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS) Intron (51 - 142)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005074