Standard Name	CPR7
Systematic Name	YJR032W
Feature Type	ORF, Verified
Description	Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity (1)
Name Description	Cyclosporin-sensitive Proline Rotamase

Chromosomal Location	ChrX:491081 to 492262 | ORF Map | GBrowse

	View Computational GO annotations for CPR7
Molecular Function
Manually curated	peptidyl-prolyl cis-trans isomerase activity (IDA) unfolded protein binding (IDA)
Biological Process
Manually curated	protein refolding (IDA) response to stress (IGI, IMP)
Cellular Component
Manually curated	cytosol (IPI)

Classical genetics
null	freeze-thaw resistance: decreased growth in exponential phase: decreased rate resistance to cycloheximide: decreased resistance to hygromycin: decreased resistance to azetidine-2-carboxylic acid: decreased viable
Large-scale survey
null	competitive fitness: decreased heat sensitivity: increased metal resistance: increased mitochondrial genome maintenance: abnormal resistance to benzo[a]pyrene: decreased resistance to sorbate: decreased resistance to glucose: decreased resistance to nickel sulfate: decreased resistance to amiodarone: decreased resistance to hygromycin B: decreased resistance to cycloheximide: decreased resistance to paromomycin: decreased respiratory growth: decreased rate sporulation efficiency: increased stress resistance: increased transposable element transposition: decreased vacuolar morphology: abnormal vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	243 total interaction(s) for 154 unique genes/features.
Physical Interactions	Affinity Capture-MS: 15 Affinity Capture-RNA: 2 Affinity Capture-Western: 16 Biochemical Activity: 1 Co-fractionation: 1 Protein-RNA: 1 Reconstituted Complex: 4 Two-hybrid: 3
Genetic Interactions	Dosage Rescue: 4 Negative Genetic: 120 Phenotypic Enhancement: 5 Phenotypic Suppression: 1 Positive Genetic: 34 Synthetic Growth Defect: 21 Synthetic Lethality: 14 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrX:491081 to 492262 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1182 491081..492262 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003793