CPR6/YLR216C Summary Help

CPR6 BASIC INFORMATION

Standard Name CPR6
Systematic Name YLR216C
Alias CYP40 1
Feature Type ORF, Verified
Description Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity (2)
Name Description Cyclosporin-sensitive Proline Rotamase
GO Annotations All CPR6 GO evidence and references
    View Computational GO annotations for CPR6
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All CPR6 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions CPR6 All interactions details and references
66 total interaction(s) for 46 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 30
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Biochemical Activity: 1
  • PCA: 3
  • Reconstituted Complex: 6
  • Two-hybrid: 5

Genetic Interactions
  • Dosage Rescue: 2
  • Phenotypic Enhancement: 7
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 6

Sequence Information
ChrXII:573213 to 572098 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2004-02-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1116 573213..572098 2004-02-05 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004206

CPR6 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Functional Analysis

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Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CPR6]

1) Warth R, et al.  (1997) Functional analysis of the yeast 40 kDa cyclophilin Cyp40 and its role for viability and steroid receptor regulation. Biol Chem 378(5):381-91
2) Mayr C, et al.  (2000) Cpr6 and Cpr7, two closely related Hsp90-associated immunophilins from Saccharomyces cerevisiae, differ in their functional properties. J Biol Chem 275(44):34140-6