CPR3/YML078W Summary

CPR3 BASIC INFORMATION

Standard Name	CPR3
Systematic Name	YML078W
Alias	CYP3
Feature Type	ORF, Verified
Description	Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; involved in protein refolding after import into mitochondria (1)
Name Description	Cyclosporin-sensitive Proline Rotamase

GO Annotations	All CPR3 GO evidence and references
	View Computational GO annotations for CPR3
Molecular Function
Manually curated	peptidyl-prolyl cis-trans isomerase activity (IDA)
Biological Process
Manually curated	apoptosis (IMP) protein folding (IDA)
Cellular Component
Manually curated	mitochondrion (IDA)
High-throughput	mitochondrion (IDA)

Mutant Phenotype	All CPR3 Phenotype details and references
Classical genetics
null	viable
Large-scale survey
null	apoptosis: decreased resistance to citric acid: decreased resistance to ethanol: decreased viable
overexpression	filamentous growth: increased

Interactions	CPR3 All interactions details and references
	3 total interaction(s) for 3 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Affinity Capture-RNA: 1

Sequence Information

ChrXIII:111002 to 111550 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..549	111002..111550	1996-07-31	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004543

CPR3 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for CPR3

NOMENCLATURE CONFLICT NOTE

Name	Relevance	Description
CYC7	Nomenclature conflict	CYP3 has been used to refer to both CYC7/YEL039C, which encodes an isoform of cytochrome c, and CPR3/YML078W, which encodes a peptidyl-prolyl cis-trans isomerase.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CPR3]

1)	Matouschek A, et al. (1995) Cyclophilin catalyzes protein folding in yeast mitochondria. Proc Natl Acad Sci U S A 92(14):6319-23

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