COX19/YLL018C-A Summary Help

Standard Name COX19 1
Systematic Name YLL018C-A
Feature Type ORF, Verified
Description Protein required for cytochrome c oxidase assembly; located in the cytosol and mitochondrial intermembrane space; putative copper metallochaperone that delivers copper to cytochrome c oxidase; contains twin cysteine-x9-cysteine motifs (1, 2)
Name Description Cytochrome c OXidase 1
Chromosomal Location
ChrXII:108972 to 108676 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All COX19 GO evidence and references
  View Computational GO annotations for COX19
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Classical genetics
null
reduction of function
Large-scale survey
null
Resources
9 total interaction(s) for 8 unique genes/features.
Physical Interactions
  • Affinity Capture-Western: 1
  • Biochemical Activity: 1
  • Co-purification: 2

Genetic Interactions
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 98
Molecular Weight (Da) 11,105
Isoelectric Point (pI) 5.17
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:108972 to 108676 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1999-07-17
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..297 108972..108676 2011-02-03 1999-07-17
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000007245
References cited on this page View Complete Literature Guide for COX19
1) Nobrega MP, et al.  (2002) Characterization of COX19, a widely distributed gene required for expression of mitochondrial cytochrome oxidase. J Biol Chem 277(43):40206-11
2) Longen S, et al.  (2009) Systematic analysis of the twin cx(9)c protein family. J Mol Biol 393(2):356-68