COQ4/YDR204W Summary Help

Standard Name COQ4 1
Systematic Name YDR204W
Feature Type ORF, Verified
Description Protein with a role in ubiquinone (Coenzyme Q) biosynthesis; possibly functioning in stabilization of Coq7p; located on the matrix face of the mitochondrial inner membrane; component of a mitochondrial ubiquinone-synthesizing complex (1, 2, 3)
Name Description COenzyme Q 1
Chromosomal Location
ChrIV:858137 to 859144 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All COQ4 GO evidence and references
  View Computational GO annotations for COQ4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 5 genes
Resources
Classical genetics
null
reduction of function
Large-scale survey
null
Resources
55 total interaction(s) for 49 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 2
  • Co-fractionation: 3

Genetic Interactions
  • Dosage Growth Defect: 1
  • Negative Genetic: 23
  • Phenotypic Enhancement: 2
  • Phenotypic Suppression: 3
  • Positive Genetic: 17

Resources
Expression Summary
histogram
Resources
Length (a.a.) 335
Molecular Weight (Da) 38,627
Isoelectric Point (pI) 10.48
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:858137 to 859144 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1008 858137..859144 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002612
References cited on this page View Complete Literature Guide for COQ4
1) Belogrudov GI, et al.  (2001) Yeast COQ4 encodes a mitochondrial protein required for coenzyme Q synthesis. Arch Biochem Biophys 392(1):48-58
2) Marbois B, et al.  (2005) Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q. J Biol Chem 280(21):20231-8
3) Hsieh EJ, et al.  (2007) Saccharomyces cerevisiae Coq9 polypeptide is a subunit of the mitochondrial coenzyme Q biosynthetic complex. Arch Biochem Biophys 463(1):19-26