COP1/YDL145C Summary Help

Standard Name COP1
Systematic Name YDL145C
Alias SEC33 , RET1 , SOO1 1
Feature Type ORF, Verified
Description Alpha subunit of COPI vesicle coatomer complex; complex surrounds transport vesicles in the early secretory pathway (2)
Name Description COat Protein
Chromosomal Location
ChrIV:198176 to 194571 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All COP1 GO evidence and references
  View Computational GO annotations for COP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
conditional
repressible
Large-scale survey
null
overexpression
repressible
Resources
246 total interaction(s) for 164 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 100
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 13
  • Co-crystal Structure: 1
  • Protein-peptide: 3
  • Reconstituted Complex: 3
  • Two-hybrid: 4

Genetic Interactions
  • Dosage Growth Defect: 3
  • Dosage Lethality: 2
  • Dosage Rescue: 4
  • Negative Genetic: 87
  • Phenotypic Suppression: 1
  • Positive Genetic: 8
  • Synthetic Growth Defect: 6
  • Synthetic Haploinsufficiency: 1
  • Synthetic Lethality: 8

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,201
Molecular Weight (Da) 135,606
Isoelectric Point (pI) 5.88
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:198176 to 194571 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3606 198176..194571 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002304
References cited on this page View Complete Literature Guide for COP1
1) Lee DW, et al.  (1999) Identification of a gene, SOO1, which complements osmo-sensitivity and defect in in vitro beta1,3-glucan synthase activity in Saccharomyces cerevisiae. Biochim Biophys Acta 1450(2):145-54
2) Gerich B, et al.  (1995) Non-clathrin-coat protein alpha is a conserved subunit of coatomer and in Saccharomyces cerevisiae is essential for growth. Proc Natl Acad Sci U S A 92(8):3229-33