COG8/YML071C Summary

COG8 BASIC INFORMATION

Standard Name	COG8 1
Systematic Name	YML071C
Alias	DOR1
Feature Type	ORF, Verified
Description	Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments (1, 2)
Name Description	Conserved Oligomeric Golgi complex 1

GO Annotations	All COG8 GO evidence and references
	View Computational GO annotations for COG8
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	intra-Golgi vesicle-mediated transport (IGI, IPI)
Cellular Component
Manually curated	Golgi transport complex (IPI)

Mutant Phenotype	All COG8 Phenotype details and references
Large-scale survey
null	alkaline pH resistance: decreased metal resistance: decreased resistance to hygromycin B: decreased resistance to monensin: decreased viable

Interactions	COG8 All interactions details and references
	235 total interaction(s) for 116 unique genes/features.
Physical Interactions	Affinity Capture-MS: 40 Affinity Capture-Western: 8 Two-hybrid: 3
Genetic Interactions	Phenotypic Enhancement: 153 Phenotypic Suppression: 5 Synthetic Growth Defect: 8 Synthetic Lethality: 18

Sequence Information

ChrXIII:131572 to 129749 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1824	131572..129749	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004536

COG8 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for COG8

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for COG8]

1)	Ram RJ, et al. (2002) Identification of Sec36p, Sec37p, and Sec38p: components of yeast complex that contains Sec34p and Sec35p. Mol Biol Cell 13(5):1484-500
2)	Loh E and Hong W (2004) The binary interacting network of the conserved oligomeric Golgi tethering complex. J Biol Chem 279(23):24640-8

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