COG5/YNL051W Summary

COG5 BASIC INFORMATION

Standard Name	COG5 1
Systematic Name	YNL051W
Alias	API4 2 , COD4
Feature Type	ORF, Verified
Description	Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments (1, 3)
Name Description	Conserved Oligomeric Golgi complex 1

GO Annotations	All COG5 GO evidence and references
	View Computational GO annotations for COG5
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	intra-Golgi vesicle-mediated transport (IGI, IPI)
Cellular Component
Manually curated	Golgi transport complex (IPI)

Mutant Phenotype	All COG5 Phenotype details and references
Large-scale survey
null	competitive fitness: decreased hyperosmotic stress resistance: decreased metal resistance: decreased resistance to hygromycin B: decreased resistance to 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid: decreased resistance to PM02734: decreased resistance to ethanol: decreased viable

Interactions	COG5 All interactions details and references
	181 total interaction(s) for 82 unique genes/features.
Physical Interactions	Affinity Capture-MS: 25 Affinity Capture-Western: 11 Two-hybrid: 5
Genetic Interactions	Phenotypic Enhancement: 113 Phenotypic Suppression: 4 Synthetic Growth Defect: 11 Synthetic Lethality: 12

Sequence Information

ChrXIV:532661 to 533872 | |

Last Update

Coordinates: 2010-01-05 | Sequence: 1997-01-28

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1212	532661..533872	2010-01-05	1997-01-28

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004996

COG5 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for COG5

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for COG5]

1)	Ram RJ, et al. (2002) Identification of Sec36p, Sec37p, and Sec38p: components of yeast complex that contains Sec34p and Sec35p. Mol Biol Cell 13(5):1484-500
2)	Bidlingmaier S and Snyder M (2002) Large-scale identification of genes important for apical growth in Saccharomyces cerevisiae by directed allele replacement technology (DART) screening. Funct Integr Genomics 1(6):345-56
3)	Loh E and Hong W (2004) The binary interacting network of the conserved oligomeric Golgi tethering complex. J Biol Chem 279(23):24640-8

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