CNB1/YKL190W Summary Help

CNB1 BASIC INFORMATION

Standard Name CNB1 1
Systematic Name YKL190W
Alias CRV1 , YCN2
Feature Type ORF, Verified
Description Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is encoded by CNA1 and/or CMP1 (2, 3)
Name Description CalciNeurin subunit B
GO Annotations All CNB1 GO evidence and references
    View Computational GO annotations for CNB1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All CNB1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions CNB1 All interactions details and references
111 total interaction(s) for 83 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 9
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1
  • PCA: 1
  • Two-hybrid: 4
Genetic Interactions
  • Dosage Rescue: 10
  • Phenotypic Enhancement: 12
  • Phenotypic Suppression: 7
  • Synthetic Growth Defect: 5
  • Synthetic Lethality: 53
  • Synthetic Rescue: 7
Sequence Information
ChrXI:82952 to 83555 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-02-13 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..52 82952..83003 2004-02-13 1996-07-31
Intron 53..128 83004..83079 2004-02-13 1996-07-31
CDS 129..604 83080..83555 2004-02-13 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001673

CNB1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for CNB1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CNB1]

1) Cyert MS and Thorner J  (1992) Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone. Mol Cell Biol 12(8):3460-9
2) Cyert MS  (2003) Calcineurin signaling in Saccharomyces cerevisiae: how yeast go crazy in response to stress. Biochem Biophys Res Commun 311(4):1143-50
3) Rusnak F and Mertz P  (2000) Calcineurin: form and function. Physiol Rev 80(4):1483-521