CMK1/YFR014C Summary Help

CMK1 BASIC INFORMATION

Standard Name CMK1 1, 2
Systematic Name YFR014C
Feature Type ORF, Verified
Description Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to Cmk2p and mammalian Cam Kinase II (1, 2, 3)
Name Description CalModulin dependent protein Kinase 1, 2
GO Annotations All CMK1 GO evidence and references
    View Computational GO annotations for CMK1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulatory Role
Regulatory modules predicted: stressResponse ( 619 , 583 , 505 , 361 )
Mutant Phenotype All CMK1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions CMK1 All interactions details and references
179 total interaction(s) for 175 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 158
  • Reconstituted Complex: 1
Genetic Interactions
  • Phenotypic Enhancement: 5
  • Phenotypic Suppression: 8
  • Synthetic Growth Defect: 2
Sequence Information
ChrVI:173869 to 172529 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2003-09-26 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1341 173869..172529 2003-09-26 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001910

CMK1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
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  • Protein Info & Structure
  • Localization Resources
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  • Phenotype Resources
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for CMK1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CMK1]

1) Pausch MH, et al.  (1991) Multiple Ca2+/calmodulin-dependent protein kinase genes in a unicellular eukaryote. EMBO J 10(6):1511-22
2) Ohya Y, et al.  (1991) Two yeast genes encoding calmodulin-dependent protein kinases. Isolation, sequencing and bacterial expressions of CMK1 and CMK2. J Biol Chem 266(19):12784-94
3) Cyert MS  (2001) Genetic analysis of calmodulin and its targets in Saccharomyces cerevisiae. Annu Rev Genet 35:647-72