CKB2/YOR039W Summary Help

CKB2 BASIC INFORMATION

Standard Name CKB2
Systematic Name YOR039W
Feature Type ORF, Verified
Description Beta' regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKA2 and CKB1, the many substrates include transcription factors and all RNA polymerases (1, 2, 3)
Name Description Casein Kinase Beta' subunit
GO Annotations All CKB2 GO evidence and references
    View Computational GO annotations for CKB2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All CKB2 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions CKB2 All interactions details and references
278 total interaction(s) for 161 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 84
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 5
  • Biochemical Activity: 5
  • Co-purification: 1
  • PCA: 3
  • Reconstituted Complex: 2
  • Two-hybrid: 5
Genetic Interactions
  • Dosage Rescue: 2
  • Phenotypic Enhancement: 123
  • Phenotypic Suppression: 25
  • Synthetic Growth Defect: 17
  • Synthetic Lethality: 4
  • Synthetic Rescue: 1
Sequence Information
ChrXV:405768 to 406544 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..777 405768..406544 2006-01-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005565

CKB2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for CKB2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CKB2]

1) Bidwai AP, et al.  (1994) Casein kinase II of Saccharomyces cerevisiae contains two distinct regulatory subunits, beta and beta'. Arch Biochem Biophys 309(2):348-55
2) Ackermann K, et al.  (2001) Genes targeted by protein kinase CK2: a genome-wide expression array analysis in yeast. Mol Cell Biochem 227(1-2):59-66
3) Ahmed K, et al.  (2002) Joining the cell survival squad: an emerging role for protein kinase CK2. Trends Cell Biol 12(5):226-30