| Standard Name | CIR1 1 |
|---|---|
| Systematic Name | YGR207C |
| Feature Type | ORF, Verified |
| Description | Mitochondrial protein that interacts with frataxin (Yfh1p); putative ortholog of mammalian electron transfer flavoprotein complex subunit ETF-beta; may have a role in oxidative stress response (1, 2, 3) |
| Name Description | Changed Intracellular Redox state 1 |
| Chromosomal Location | |
|---|---|
| Note: this feature is encoded on the Crick strand. | |
Gene Ontology Annotations All CIR1 GO evidence and references
| View Computational GO annotations for CIR1 | |
| Molecular Function | |
| Manually curated |
|
| Biological Process | |
| Manually curated |
|
| Cellular Component | |
| High-throughput |
Mutant phenotypes All CIR1 Phenotype evidence and references
| Classical genetics | |
|---|---|
| null |
|
| Large-scale survey | |
| null |
|
| Resources |
interactions All CIR1 Interaction evidence and references
| 15 total interaction(s) for 15 unique genes/features. | |
| Physical Interactions |
|
| Genetic Interactions |
|
| Resources |
|
Expression Summary
|
| |
| Resources |
Protein Information All CIR1 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
|
| |||||||||||||
| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
| ||||||||||||
| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
|---|
| Primary SGDID | S000003439 |
|---|
References cited on this page View Complete Literature Guide for CIR1
| 1) | Lopes J, et al. (2010) The Saccharomyces cerevisiae Genes, AIM45, YGR207c/CIR1 and YOR356w/CIR2, Are Involved in Cellular Redox State Under Stress Conditions. Open Microbiol J 4():75-82 |
| 2) | Gonzalez-Cabo P, et al. (2005) Frataxin interacts functionally with mitochondrial electron transport chain proteins. Hum Mol Genet 14(15):2091-8 |
| 3) | Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 |





