CIR1/YGR207C Summary Help

Standard Name CIR1 1
Systematic Name YGR207C
Feature Type ORF, Verified
Description Mitochondrial protein that interacts with frataxin (Yfh1p); putative ortholog of mammalian electron transfer flavoprotein complex subunit ETF-beta; may have a role in oxidative stress response (1, 2, 3)
Name Description Changed Intracellular Redox state 1
Chromosomal Location
ChrVII:911628 to 910843 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All CIR1 GO evidence and references
  View Computational GO annotations for CIR1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 6 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
15 total interaction(s) for 15 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 8
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1

Genetic Interactions
  • Negative Genetic: 2
  • Positive Genetic: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 261
Molecular Weight (Da) 28,758
Isoelectric Point (pI) 8.71
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:911628 to 910843 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..786 911628..910843 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003439
References cited on this page View Complete Literature Guide for CIR1
1) Lopes J, et al.  (2010) The Saccharomyces cerevisiae Genes, AIM45, YGR207c/CIR1 and YOR356w/CIR2, Are Involved in Cellular Redox State Under Stress Conditions. Open Microbiol J 4():75-82
2) Gonzalez-Cabo P, et al.  (2005) Frataxin interacts functionally with mitochondrial electron transport chain proteins. Hum Mol Genet 14(15):2091-8
3) Reinders J, et al.  (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54