CHS1/YNL192W Summary Help

Standard Name CHS1
Systematic Name YNL192W
Alias USA4 1
Feature Type ORF, Verified
Description Chitin synthase I; requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for repairing the chitin septum during cytokinesis; transcription activated by mating factor (2, 3, 4)
Name Description CHitin Synthase
Chromosomal Location
ChrXIV:276502 to 279897 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All CHS1 GO evidence and references
  View Computational GO annotations for CHS1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 8 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
Resources
180 total interaction(s) for 123 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 10
  • Affinity Capture-RNA: 3
  • Biochemical Activity: 4
  • Co-fractionation: 2
  • PCA: 2
  • Reconstituted Complex: 1

Genetic Interactions
  • Negative Genetic: 23
  • Phenotypic Suppression: 1
  • Positive Genetic: 16
  • Synthetic Growth Defect: 34
  • Synthetic Haploinsufficiency: 1
  • Synthetic Lethality: 82
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,131
Molecular Weight (Da) 129,870
Isoelectric Point (pI) 6.15
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:276502 to 279897 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3396 276502..279897 2011-02-03 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005136
References cited on this page View Complete Literature Guide for CHS1
1) Awasthi S, et al.  (2001) New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing. J Biol Chem 276(33):31004-15
2) Cabib E, et al.  (1992) Chitinase and chitin synthase 1: counterbalancing activities in cell separation of Saccharomyces cerevisiae. J Gen Microbiol 138(1):97-102
3) Ziman M, et al.  (1996) Chs1p and Chs3p, two proteins involved in chitin synthesis, populate a compartment of the Saccharomyces cerevisiae endocytic pathway. Mol Biol Cell 7(12):1909-19
4) Cid VJ, et al.  (1995) Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiae. Microbiol Rev 59(3):345-86