Standard Name	CHO1 1
Systematic Name	YER026C
Alias	PSS1
Feature Type	ORF, Verified
Description	Phosphatidylserine synthase, functions in phospholipid biosynthesis; catalyzes the reaction CDP-diaclyglycerol + L-serine = CMP + L-1-phosphatidylserine, transcriptionally repressed by myo-inositol and choline (1, 2, 3, 4, 5)
Name Description	CHOline requiring 3

Chromosomal Location	ChrV:208474 to 207644 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 22 cM

	View Computational GO annotations for CHO1
Molecular Function
Manually curated	CDP-diacylglycerol-serine O-phosphatidyltransferase activity (IDA, IMP)
Biological Process
Manually curated	phosphatidylserine biosynthetic process (IDA, IMP)
Cellular Component
Manually curated	NOT endoplasmic reticulum (IDA) integral to membrane (IDA) mitochondrial outer membrane (IDA)

Pathways	phosphatidic acid and phospholipid biosynthesis phospholipid biosynthesis superpathway of phospholipid biosynthesis

Classical genetics
null	auxotrophy killer toxin resistance: increased Arn1p distribution: abnormal
unspecified	auxotrophy
Large-scale survey
null	acid pH resistance: decreased resistance to 2,4-Diacetylphloroglucinol: decreased resistance to boric acid: decreased resistance to CTBT: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	42 total interaction(s) for 38 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 PCA: 18 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 6 Phenotypic Enhancement: 3 Phenotypic Suppression: 2 Synthetic Growth Defect: 5 Synthetic Lethality: 2 Synthetic Rescue: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrV:208474 to 207644 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 22 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..831 208474..207644 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000828