CDS1/YBR029C Summary Help

Standard Name CDS1 1
Systematic Name YBR029C
Alias CDG1
Feature Type ORF, Verified
Description Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); an enzyme that catalyzes that conversion of CTP + phosphate into diphosphate + CDP-diaclglyerol, a critical step in the synthesis of all major yeast phospholipids (1, 2)
Name Description CDP-Diacylglycerol Synthase 1
Chromosomal Location
ChrII:297742 to 296369 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All CDS1 GO evidence and references
  View Computational GO annotations for CDS1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 9 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
conditional
null
overexpression
reduction of function
repressible
Resources
30 total interaction(s) for 27 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 2
  • PCA: 1
  • Protein-RNA: 1
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 9
  • Positive Genetic: 6
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 457
Molecular Weight (Da) 51,822
Isoelectric Point (pI) 8.64
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:297742 to 296369 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2004-07-16 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1374 297742..296369 2004-07-16 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000233
References cited on this page View Complete Literature Guide for CDS1
1) Shen H, et al.  (1996) The CDS1 gene encoding CDP-diacylglycerol synthase in Saccharomyces cerevisiae is essential for cell growth. J Biol Chem 271(2):789-95
2) Shen H and Dowhan W  (1997) Regulation of phospholipid biosynthetic enzymes by the level of CDP-diacylglycerol synthase activity. J Biol Chem 272(17):11215-20