CDC65/tQ(CUG)M Summary Help

Standard Name CDC65 1, 2
Systematic Name tQ(CUG)M
Alias DNA33 3 , SUP70 4 , SUP60 5
Feature Type tRNA
Description Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE analysis; can mutate to cause constitutive pseudohyphal growth in homozygous diploids (4, 6, 7, 8)
Name Description Cell Division Cycle
Chromosomal Location
ChrXIII:808317 to 808246 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Genetic position: 187 cM
Gene Ontology Annotations All CDC65 GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Classical genetics
reduction of function
5 total interaction(s) for 5 unique genes/features.
Physical Interactions
  • Reconstituted Complex: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 2

sequence information
ChrXIII:808317 to 808246 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Genetic position: 187 cM
Last Update Coordinates: 2011-02-03 | Sequence: 2000-05-19
Subfeature details
Most Recent Updates
Coordinates Sequence
Noncoding exon 1..72 808317..808246 2011-02-03 2000-05-19
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
External Links All Associated Seq | Search all NCBI (Entrez)
Primary SGDIDS000006690
References cited on this page View Complete Literature Guide for CDC65
1) Prendergast JA, et al.  (1990) Size selection identifies new genes that regulate Saccharomyces cerevisiae cell proliferation. Genetics 124(1):81-90
2) Johnston, G.  (1989) Personal Communication, Mortimer Map Edition 10
3) Dumas LB, et al.  (1982) New temperature-sensitive mutants of Saccharomyces cerevisiae affecting DNA replication. Mol Gen Genet 187(1):42-6
4) Beeser AE and Cooper TG  (1999) Control of nitrogen catabolite repression is not affected by the tRNAGln-CUU mutation, which results in constitutive pseudohyphal growth of Saccharomyces cerevisiae. J Bacteriol 181(8):2472-6
5) Winey M, et al.  (1989) A synthetic intron in a naturally intronless yeast pre-tRNA is spliced efficiently in vivo. Mol Cell Biol 9(1):329-31
6) Murray LE, et al.  (1998) A yeast glutamine tRNA signals nitrogen status for regulation of dimorphic growth and sporulation. Proc Natl Acad Sci U S A 95(15):8619-24
7) Percudani R, et al.  (1997) Transfer RNA gene redundancy and translational selection in Saccharomyces cerevisiae. J Mol Biol 268(2):322-30
8) Chan PP and Lowe TM  (2009) GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res 37(Database issue):D93-7