CDC65/tQ(CUG)M Summary

CDC65/tQ(CUG)M Summary

Standard Name	CDC65 1, 2
Systematic Name	tQ(CUG)M
Alias	DNA33 3 , SUP70 , SUP60 4
Feature Type	tRNA
Description	Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE analysis; can mutate to cause constitutive pseudohyphal growth in homozygous diploids (5, 6, 7, 8)
Name Description	Cell Division Cycle

Chromosomal Location	ChrXIII:808317 to 808246 \| ORF Map \| GBrowse
	Note: this feature is encoded on the Crick strand.

	Genetic position: 187 cM

Gene Ontology Annotations All CDC65 GO evidence and references


Molecular Function
Manually curated	triplet codon-amino acid adaptor activity (TAS)
Biological Process
Manually curated	mitochondrial translational elongation (IGI)
Cellular Component
Manually curated	cytosol (IDA) mitochondrion (IDA)

Mutant phenotypes All CDC65 Phenotype evidence and references

Classical genetics
conditional	cell cycle progression in G1 phase: arrested cellular morphology: abnormal heat sensitivity: increased

interactions All CDC65 Interaction evidence and references

	5 total interaction(s) for 5 unique genes/features.
Physical Interactions	Reconstituted Complex: 1
Genetic Interactions	Dosage Rescue: 1 Synthetic Growth Defect: 1 Synthetic Lethality: 2
Resources	BioGRID

sequence information

ChrXIII:808317 to 808246 | |

Note: this feature is encoded on the Crick strand.

SGD ORF map

: 187 cM

Last Update

Coordinates: 2011-02-03 | Sequence: 2000-05-19

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
Noncoding exon	1..72	808317..808246	2011-02-03	2000-05-19

Retrieve sequences

Analyze Sequence

S288C only	ATCC/WashU Clones \| BLASTN \| Design Primers \| Restriction Fragment Map \| Restriction Fragment Sizes
S288C vs. other species	BLASTN vs. fungi

Resources

External Links	All Associated Seq \| Search all NCBI (Entrez)

Primary SGDID	S000006690

References cited on this page View Complete Literature Guide for CDC65

1)	Prendergast JA, et al. (1990) Size selection identifies new genes that regulate Saccharomyces cerevisiae cell proliferation. Genetics 124(1):81-90
2)	Johnston, G. (1989) Personal Communication, Mortimer Map Edition 10
3)	Dumas LB, et al. (1982) New temperature-sensitive mutants of Saccharomyces cerevisiae affecting DNA replication. Mol Gen Genet 187(1):42-6
4)	Winey M, et al. (1989) A synthetic intron in a naturally intronless yeast pre-tRNA is spliced efficiently in vivo. Mol Cell Biol 9(1):329-31
5)	Murray LE, et al. (1998) A yeast glutamine tRNA signals nitrogen status for regulation of dimorphic growth and sporulation. Proc Natl Acad Sci U S A 95(15):8619-24
6)	Beeser AE and Cooper TG (1999) Control of nitrogen catabolite repression is not affected by the tRNAGln-CUU mutation, which results in constitutive pseudohyphal growth of Saccharomyces cerevisiae. J Bacteriol 181(8):2472-6
7)	Percudani R, et al. (1997) Transfer RNA gene redundancy and translational selection in Saccharomyces cerevisiae. J Mol Biol 268(2):322-30
8)	Chan PP and Lowe TM (2009) GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res 37(Database issue):D93-7