Standard Name	CDC55 1
Systematic Name	YGL190C
Feature Type	ORF, Verified
Description	Non-essential regulatory subunit B of protein phosphatase 2A (PP2A); localization to the cytoplasm requires Zds1p and Zds2p and promotes mitotic entry; localization to the nucleus prevents mitotic exit; required for correct nuclear division and chromosome segregation in meiosis; maintains nucleolar sequestration of Cdc14p during early meiosis; limits formation of PP2A-Rts1p holocomplexes to ensure timely dissolution of sister chromosome cohesion (2, 3, 4, 5, 6, 7)
Name Description	Cell Division Cycle

Chromosomal Location	ChrVII:147389 to 145809 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: -125 cM

	View Computational GO annotations for CDC55
Molecular Function
Manually curated	protein phosphatase type 2A regulator activity (IPI, ISA)
Biological Process
Manually curated	cell shape checkpoint (IGI) negative regulation of exit from mitosis (IMP) positive regulation of G2/M transition of mitotic cell cycle (IMP) protein dephosphorylation (TAS)
Cellular Component
Manually curated	cellular bud neck (IDA) cellular bud tip (IDA) cytoplasm (IDA) nucleus (IDA)

Regulatory modules	predicted: cellcycle (263)

Classical genetics
conditional	bud morphology: abnormal growth in exponential phase: decreased rate
null	bud morphology: abnormal cold sensitivity: increased gamma ray resistance: decreased ZDS1-GFP distribution: abnormal CDC28 modification: increased resistance to nocodazole: decreased resistance to hydroxyurea: decreased resistance to benomyl: decreased viable
repressible	meiosis: abnormal Cdc14p distribution: abnormal
unspecified	pseudohyphal growth: absent
Large-scale survey
null	filamentous growth: decreased invasive growth: absent
overexpression	cell cycle progression: abnormal
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	296 total interaction(s) for 193 unique genes/features.
Physical Interactions	Affinity Capture-MS: 77 Affinity Capture-RNA: 1 Affinity Capture-Western: 18 Biochemical Activity: 5 Protein-RNA: 1 Reconstituted Complex: 1 Two-hybrid: 16
Genetic Interactions	Dosage Growth Defect: 4 Dosage Lethality: 8 Dosage Rescue: 5 Negative Genetic: 42 Phenotypic Enhancement: 9 Phenotypic Suppression: 22 Positive Genetic: 44 Synthetic Growth Defect: 12 Synthetic Lethality: 14 Synthetic Rescue: 17
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVII:147389 to 145809 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: -125 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1581 147389..145809 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003158