CDC31/YOR257W Summary Help

CDC31 BASIC INFORMATION

Standard Name CDC31
Systematic Name YOR257W
Alias DSK1
Feature Type ORF, Verified
Description Calcium-binding component of the spindle pole body (SPB) half-bridge, required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; binds multiubiquitinated proteins and is involved in proteasomal protein degradation (1, 2, 3)
Name Description Cell Division Cycle 4
GO Annotations All CDC31 GO evidence and references
    View Computational GO annotations for CDC31
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All CDC31 Phenotype details and references
Classical genetics
conditional
overexpression
Large-scale survey
null
overexpression
repressible
Interactions CDC31 All interactions details and references
90 total interaction(s) for 43 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 28
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 23
  • Biochemical Activity: 2
  • Co-localization: 1
  • Co-purification: 1
  • Far Western: 1
  • Reconstituted Complex: 10
  • Two-hybrid: 1
Genetic Interactions
  • Dosage Rescue: 11
  • Phenotypic Enhancement: 1
  • Synthetic Growth Defect: 6
  • Synthetic Lethality: 1
  • Synthetic Rescue: 3
Sequence Information
ChrXV:811008 to 811493 | ORF Map | GBrowse
Gbrowse
Genetic position: 147 cM
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..486 811008..811493 2006-01-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005783

CDC31 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for CDC31

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CDC31]

1) Spang A, et al.  (1993) The calcium-binding protein cell division cycle 31 of Saccharomyces cerevisiae is a component of the half bridge of the spindle pole body. J Cell Biol 123(2):405-16
2) Jaspersen SL, et al.  (2002) Mps3p is a novel component of the yeast spindle pole body that interacts with the yeast centrin homologue Cdc31p. J Cell Biol 159(6):945-56
3) Chen L and Madura K  (2008) Centrin/Cdc31 is a novel regulator of protein degradation. Mol Cell Biol 28(5):1829-40
4) Hartwell LH, et al.  (1970) Genetic control of the cell-division cycle in yeast. I. Detection of mutants. Proc Natl Acad Sci U S A 66(2):352-9