CDC21/YOR074C Summary Help

CDC21 BASIC INFORMATION

Standard Name CDC21
Systematic Name YOR074C
Alias CRT9 , TMP1
Feature Type ORF, Verified
Description Thymidylate synthase, required for de novo biosynthesis of pyrimidine deoxyribonucleotides; expression is induced at G1/S (1, 2)
Also known as: YOR29-25
Name Description Cell Division Cycle 3
GO Annotations All CDC21 GO evidence and references
    View Computational GO annotations for CDC21
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Pathways
Mutant Phenotype All CDC21 Phenotype details and references
Classical genetics
conditional
null
Large-scale survey
null
repressible
Interactions CDC21 All interactions details and references
11 total interaction(s) for 11 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Phenotypic Enhancement: 1
  • Synthetic Lethality: 4
  • Synthetic Rescue: 1

Sequence Information
ChrXV:467591 to 466677 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 32 cM
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..915 467591..466677 2006-01-05 2005-12-01
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005600

CDC21 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CDC21]

1) Game JC  (1976) Yeast cell-cycle mutant cdc21 is a temperature-sensitive thymidylate auxotroph. Mol Gen Genet 146(3):313-5
2) White JH, et al.  (1987) The CDC8 transcript is cell cycle regulated in yeast and is expressed coordinately with CDC9 and CDC21 at a point preceding histone transcription. Exp Cell Res 171(1):223-31
3) Hartwell LH, et al.  (1970) Genetic control of the cell-division cycle in yeast. I. Detection of mutants. Proc Natl Acad Sci U S A 66(2):352-9