CCT8/YJL008C Summary

CCT8 BASIC INFORMATION

Standard Name	CCT8
Systematic Name	YJL008C
Feature Type	ORF, Verified
Description	Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo (1, 2)
Name Description	Chaperonin Containing TCP-1

GO Annotations	All CCT8 GO evidence and references
	View Computational GO annotations for CCT8
Molecular Function
Manually curated	unfolded protein binding (IDA)
Biological Process
Manually curated	protein folding (IDA)
Cellular Component
Manually curated	chaperonin-containing T-complex (IDA, IPI)
High-throughput	cytoplasm (IDA)

Mutant Phenotype	All CCT8 Phenotype details and references
Classical genetics
null	inviable
Large-scale survey
null	inviable

Interactions	CCT8 All interactions details and references
	36 total interaction(s) for 29 unique genes/features.
Physical Interactions	Affinity Capture-MS: 28 Affinity Capture-Western: 1 Co-fractionation: 2 Co-purification: 1 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 3

Sequence Information

ChrX:421656 to 419950 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2009-02-18 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1707	421656..419950	2009-02-18	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000003545

CCT8 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for CCT8

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CCT8]

1)	Stoldt V, et al. (1996) Review: the Cct eukaryotic chaperonin subunits of Saccharomyces cerevisiae and other yeasts. Yeast 12(6):523-9
2)	Kim S, et al. (1994) Cystosolic chaperonin subunits have a conserved ATPase domain but diverged polypeptide-binding domains. Trends Biochem Sci 19(12):543-8

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