CCT6/YDR188W Summary

CCT6 BASIC INFORMATION

Standard Name	CCT6
Systematic Name	YDR188W
Alias	HTR3 , TCP6 , TCP20
Feature Type	ORF, Verified
Description	Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, essential protein that is required for the assembly of actin and tubulins in vivo; contains an ATP-binding motif (1, 2, 3)
Name Description	Chaperonin Containing TCP-1

GO Annotations	All CCT6 GO evidence and references
	View Computational GO annotations for CCT6
Molecular Function
Manually curated	unfolded protein binding (IDA)
Biological Process
Manually curated	protein folding (IDA)
Cellular Component
Manually curated	chaperonin-containing T-complex (IDA, IPI)

Mutant Phenotype	All CCT6 Phenotype details and references
Classical genetics
null	inviable
overexpression	growth in exponential phase: increased rate
Large-scale survey
null	competitive fitness: decreased haploinsufficient inviable
overexpression	vegetative growth: decreased
repressible	mitochondrial morphology: abnormal

Interactions	CCT6 All interactions details and references
	108 total interaction(s) for 94 unique genes/features.
Physical Interactions	Affinity Capture-MS: 87 Biochemical Activity: 3 Co-purification: 1 PCA: 1
Genetic Interactions	Dosage Rescue: 16

Sequence Information

ChrIV:836419 to 838059 | |

Last Update

Coordinates: 2008-06-05 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1641	836419..838059	2008-06-05	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000002596

CCT6 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for CCT6

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CCT6]

1)	Stoldt V, et al. (1996) Review: the Cct eukaryotic chaperonin subunits of Saccharomyces cerevisiae and other yeasts. Yeast 12(6):523-9
2)	Kim S, et al. (1994) Cystosolic chaperonin subunits have a conserved ATPase domain but diverged polypeptide-binding domains. Trends Biochem Sci 19(12):543-8
3)	Kabir MA, et al. (2005) Physiological effects of unassembled chaperonin Cct subunits in the yeast Saccharomyces cerevisiae. Yeast 22(3):219-39

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