CCT4/YDL143W Summary

CCT4 BASIC INFORMATION

Standard Name	CCT4
Systematic Name	YDL143W
Alias	TCP4 , ANC2 1
Feature Type	ORF, Verified
Description	Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo (1, 2)
Name Description	Chaperonin Containing TCP-1

GO Annotations	All CCT4 GO evidence and references
	View Computational GO annotations for CCT4
Molecular Function
Manually curated	unfolded protein binding (IDA)
Biological Process
Manually curated	protein folding (IDA)
Cellular Component
Manually curated	chaperonin-containing T-complex (IDA, IPI)

Mutant Phenotype	All CCT4 Phenotype details and references
Classical genetics
null	inviable
Large-scale survey
null	competitive fitness: decreased haploinsufficient inviable
repressible	mitochondrial morphology: abnormal

Interactions	CCT4 All interactions details and references
	63 total interaction(s) for 56 unique genes/features.
Physical Interactions	Affinity Capture-MS: 33 Affinity Capture-RNA: 1 Biochemical Activity: 2 Co-purification: 2 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 23 Phenotypic Suppression: 1

Sequence Information

ChrIV:199997 to 201583 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1587	199997..201583	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000002302

CCT4 RESOURCES

Click on map for expanded view

SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for CCT4

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CCT4]

1)	Vinh DB and Drubin DG (1994) A yeast TCP-1-like protein is required for actin function in vivo. Proc Natl Acad Sci U S A 91(19):9116-20
2)	Chen X, et al. (1994) Two yeast genes with similarity to TCP-1 are required for microtubule and actin function in vivo. Proc Natl Acad Sci U S A 91(19):9111-5

SGD^tm pages Database Copyright © 1997-2010 The Board of Trustees of Leland Stanford Junior University. Permission to use the information contained in this database was given by the researchers/institutes who contributed or published the information. Users of the database are solely responsible for compliance with any copyright restrictions, including those applying to the author abstracts. Documents from this server are provided "AS-IS" without any warranty, expressed or implied. The SGD project at Stanford University is supported by a Genome Research Resource Grant from the US National Human Genome Research Institute, part of the US National Institutes of Health.