CCT2/YIL142W Summary

CCT2 BASIC INFORMATION

Standard Name	CCT2
Systematic Name	YIL142W
Alias	BIN3 , TCP2
Feature Type	ORF, Verified
Description	Subunit beta of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo (1, 2)
Name Description	Chaperonin Containing TCP-1

GO Annotations	All CCT2 GO evidence and references
	View Computational GO annotations for CCT2
Molecular Function
Manually curated	unfolded protein binding (IDA)
Biological Process
Manually curated	protein folding (IDA)
Cellular Component
Manually curated	chaperonin-containing T-complex (IDA, IPI)
High-throughput	cytoplasm (IDA)

Mutant Phenotype	All CCT2 Phenotype details and references
Classical genetics
null	inviable
Large-scale survey
null	competitive fitness: decreased haploinsufficient inviable

Interactions	CCT2 All interactions details and references
	64 total interaction(s) for 51 unique genes/features.
Physical Interactions	Affinity Capture-MS: 40 Affinity Capture-Western: 2 Biochemical Activity: 1 Co-purification: 1 Reconstituted Complex: 1
Genetic Interactions	Dosage Rescue: 14 Synthetic Lethality: 5

Sequence Information

ChrIX:83302 to 84885 | |

Last Update

Coordinates: 1994-12-10 | Sequence: 1994-12-10

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1584	83302..84885	1994-12-10	1994-12-10

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001404

CCT2 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for CCT2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CCT2]

1)	Chen X, et al. (1994) Two yeast genes with similarity to TCP-1 are required for microtubule and actin function in vivo. Proc Natl Acad Sci U S A 91(19):9111-5
2)	Vinh DB and Drubin DG (1994) A yeast TCP-1-like protein is required for actin function in vivo. Proc Natl Acad Sci U S A 91(19):9116-20

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