Standard Name	CCT2
Systematic Name	YIL142W
Alias	BIN3 , TCP2
Feature Type	ORF, Verified
Description	Subunit beta of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo (1, 2)
Name Description	Chaperonin Containing TCP-1

Chromosomal Location	ChrIX:83302 to 84885 | ORF Map | GBrowse

	View Computational GO annotations for CCT2
Molecular Function
Manually curated	unfolded protein binding (IDA)
Biological Process
Manually curated	protein folding (IDA)
Cellular Component
Manually curated	chaperonin-containing T-complex (IDA, IPI)
High-throughput	cytoplasm (IDA)

Classical genetics
null	inviable
reduction of function	resistance to hygromycin: decreased resistance to cycloheximide: decreased resistance to azetidine-2-carboxylic acid: decreased
Large-scale survey
null	competitive fitness: decreased haploinsufficient inviable toxin resistance: decreased
reduction of function	competitive fitness: decreased resistance to methyl methanesulfonate: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	96 total interaction(s) for 76 unique genes/features.
Physical Interactions	Affinity Capture-MS: 59 Affinity Capture-RNA: 3 Affinity Capture-Western: 3 Biochemical Activity: 1 Co-fractionation: 1 Co-purification: 1 Reconstituted Complex: 1
Genetic Interactions	Dosage Rescue: 14 Synthetic Lethality: 7 Synthetic Rescue: 6
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIX:83302 to 84885 | ORF Map | GBrowse
Last Update	Coordinates: 1994-12-10 | Sequence: 1994-12-10
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1584 83302..84885 1994-12-10 1994-12-10
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001404