CCE1/YKL011C Summary Help

Standard Name CCE1 1
Systematic Name YKL011C
Alias MGT1
Feature Type ORF, Verified
Description Mitochondrial cruciform cutting endonuclease; cleaves Holliday junctions formed during recombination of mitochondrial DNA; CCE1 has a paralog, MRS1, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description Cruciform Cutting Endonuclease 1
Chromosomal Location
ChrXI:421216 to 420155 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: -2 cM
Gene Ontology Annotations All CCE1 GO evidence and references
  View Computational GO annotations for CCE1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
10 total interaction(s) for 10 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Phenotypic Enhancement: 2
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 353
Molecular Weight (Da) 41,000
Isoelectric Point (pI) 10
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:421216 to 420155 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: -2 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1062 421216..420155 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001494
References cited on this page View Complete Literature Guide for CCE1
1) Kleff S, et al.  (1992) Identification and characterization of yeast mutants and the gene for a cruciform cutting endonuclease. EMBO J 11(2):699-704
2) Ezekiel UR and Zassenhaus HP  (1993) Localization of a cruciform cutting endonuclease to yeast mitochondria. Mol Gen Genet 240(3):414-8
3) White MF and Lilley DM  (1997) The resolving enzyme CCE1 of yeast opens the structure of the four-way DNA junction. J Mol Biol 266(1):122-34
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61