CBS2/YDR197W Summary Help

Standard Name CBS2 1
Systematic Name YDR197W
Alias CBP7
Feature Type ORF, Verified
Description Mitochondrial translational activator of the COB mRNA; interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader (1, 2, 3)
Name Description Cytochrome B Synthesis 1
Chromosomal Location
ChrIV:851228 to 852397 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All CBS2 GO evidence and references
  View Computational GO annotations for CBS2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
reduction of function
Large-scale survey
null
Resources
70 total interaction(s) for 69 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 1
  • Negative Genetic: 59
  • Positive Genetic: 7

Resources
Expression Summary
histogram
Resources
Length (a.a.) 389
Molecular Weight (Da) 44,607
Isoelectric Point (pI) 10.33
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:851228 to 852397 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1170 851228..852397 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002605
References cited on this page View Complete Literature Guide for CBS2
1) Rodel G  (1986) Two yeast nuclear genes, CBS1 and CBS2, are required for translation of mitochondrial transcripts bearing the 5'-untranslated COB leader. Curr Genet 11(1):41-5
2) Michaelis U, et al.  (1991) Association of cytochrome b translational activator proteins with the mitochondrial membrane: implications for cytochrome b expression in yeast. Mol Gen Genet 230(1-2):177-85
3) Krause-Buchholz U, et al.  (2004) Saccharomyces cerevisiae translational activator Cbs2p is associated with mitochondrial ribosomes. Curr Genet 46(1):20-8