CBK1/YNL161W Summary Help

CBK1 BASIC INFORMATION

Standard Name CBK1 1
Systematic Name YNL161W
Feature Type ORF, Verified
Description Serine/threonine protein kinase that regulates cell morphogenesis pathways; involved in cell wall biosynthesis, apical growth, proper mating projection morphology, bipolar bud site selection in diploid cells, and cell separation (2, 3)
Name Description Cell wall Biosynthesis Kinase 1
GO Annotations All CBK1 GO evidence and references
    View Computational GO annotations for CBK1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All CBK1 Phenotype details and references
Classical genetics
activation
null
unspecified
Large-scale survey
null
Interactions CBK1 All interactions details and references
98 total interaction(s) for 62 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 15
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 7
  • Biochemical Activity: 2
  • Reconstituted Complex: 1
  • Two-hybrid: 22
Genetic Interactions
  • Dosage Rescue: 15
  • Phenotypic Enhancement: 8
  • Phenotypic Suppression: 3
  • Synthetic Growth Defect: 12
  • Synthetic Lethality: 10
  • Synthetic Rescue: 2
Sequence Information
ChrXIV:332599 to 334869 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2271 332599..334869 2005-11-07 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005105

CBK1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Localization Resources
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for CBK1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CBK1]

1) Geyer CR, et al.  (1999) "Mutagenesis" by peptide aptamers identifies genetic network members and pathway connections. Proc Natl Acad Sci U S A 96(15):8567-72
2) Racki WJ, et al.  (2000) Cbk1p, a protein similar to the human myotonic dystrophy kinase, is essential for normal morphogenesis in Saccharomyces cerevisiae. EMBO J 19(17):4524-32
3) Bidlingmaier S, et al.  (2001) The Cbk1p pathway is important for polarized cell growth and cell separation in Saccharomyces cerevisiae. Mol Cell Biol 21(7):2449-62