BZZ1/YHR114W Summary Help

Standard Name BZZ1 1
Systematic Name YHR114W
Alias LSB7 2
Feature Type ORF, Verified
Description SH3 domain protein implicated in regulating actin polymerization; able to recruit actin polymerization machinery through its SH3 domains; colocalizes with cortical actin patches and Las17p; interacts with type I myosins (2)
Chromosomal Location
ChrVIII:338083 to 339984 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All BZZ1 GO evidence and references
  View Computational GO annotations for BZZ1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
163 total interaction(s) for 124 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 9
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 4
  • Biochemical Activity: 3
  • PCA: 2
  • Protein-peptide: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 100

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Lethality: 1
  • Negative Genetic: 23
  • Phenotypic Enhancement: 4
  • Positive Genetic: 4
  • Synthetic Growth Defect: 6
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 633
Molecular Weight (Da) 71,171
Isoelectric Point (pI) 5.82
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:338083 to 339984 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1902 338083..339984 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001156
References cited on this page View Complete Literature Guide for BZZ1
1) Tong AH, et al.  (2002) A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules. Science 295(5553):321-4
2) Soulard A, et al.  (2002) Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro. Mol Cell Biol 22(22):7889-906