BYE1/YKL005C Summary

BYE1 BASIC INFORMATION

Standard Name	BYE1 1
Systematic Name	YKL005C
Feature Type	ORF, Verified
Description	Negative regulator of transcription elongation, contains a TFIIS-like domain and a PHD finger, multicopy suppressor of temperature-sensitive ess1 mutations, probably binds RNA polymerase II large subunit (1)
Name Description	BYpass of ESS1 1

GO Annotations	All BYE1 GO evidence and references
	View Computational GO annotations for BYE1
Molecular Function
Manually curated	methylated histone residue binding (IDA) transcription elongation regulator activity (IGI)
Biological Process
Manually curated	negative regulation of transcription from RNA polymerase II promoter (IGI)
Cellular Component
Manually curated	nucleus (TAS)

Mutant Phenotype	All BYE1 Phenotype details and references
Large-scale survey
null	resistance to ethanol: decreased viable
overexpression	vegetative growth: decreased

Interactions	BYE1 All interactions details and references
	15 total interaction(s) for 8 unique genes/features.
Physical Interactions	Affinity Capture-Luminescence: 4 Affinity Capture-MS: 2 Affinity Capture-Western: 2
Genetic Interactions	Dosage Rescue: 4 Phenotypic Enhancement: 3

Sequence Information

ChrXI:434520 to 432736 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2005-12-15 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1785	434520..432736	2005-12-15	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001488

BYE1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for BYE1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for BYE1]

1)	Wu X, et al. (2003) The ESS1 prolyl isomerase and its suppressor BYE1 interact with RNA pol II to inhibit transcription elongation in Saccharomyces cerevisiae. Genetics 165(4):1687-702

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