Standard Name	BUD8
Systematic Name	YLR353W
Feature Type	ORF, Verified
Description	Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the proximal pole; BUD8 has a paralog, BUD9, that arose from the whole genome duplication (1, 2)
Name Description	BUD site selection

Chromosomal Location	ChrXII:834352 to 836163 | ORF Map | GBrowse

	View Computational GO annotations for BUD8
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	cellular bud site selection (IMP) pseudohyphal growth (IMP)
Cellular Component
Manually curated	cellular bud tip (IDA) incipient cellular bud site (IDA) plasma membrane (IMP)

Classical genetics
null	bipolar budding pattern: decreased resistance to Calcofluor White: decreased
overexpression	cell cycle progression in G2 phase: abnormal cell size: abnormal cellular morphology: abnormal
unspecified	bipolar budding pattern: decreased pseudohyphal growth: absent resistance to caffeine: increased resistance to enzymatic treatment: decreased
Large-scale survey
null	budding pattern: abnormal cell shape: abnormal competitive fitness: increased resistance to cycloheximide: increased resistance to tunicamycin: increased resistance to bleomycin: decreased resistance to fenpropimorph: decreased resistance to fluconazole: decreased resistance to methyl methanesulfonate: decreased resistance to mycophenolic acid: decreased viable
overexpression	resistance to sirolimus: decreased vegetative growth: decreased vegetative growth: decreased rate
unspecified	filamentous growth: absent resistance to Calcofluor White: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	52 total interaction(s) for 45 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 Affinity Capture-Western: 7 Co-localization: 1 PCA: 1 Two-hybrid: 2
Genetic Interactions	Dosage Growth Defect: 3 Dosage Lethality: 1 Negative Genetic: 19 Phenotypic Enhancement: 3 Phenotypic Suppression: 7 Positive Genetic: 2 Synthetic Rescue: 5
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXII:834352 to 836163 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1812 834352..836163 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004345