Standard Name	BUD4 1
Systematic Name	YJR092W
Feature Type	ORF, Verified
Description	Anillin-like protein involved in bud-site selection; required for the axial budding pattern; localizes with septins to the bud neck in mitosis and may constitute an axial landmark for the next round of budding; required for the formation and disassembly of the double septin ring structure, and generally for septin organization; in vivo substrate of Cdc28p/Clb2p (1, 2, 3, 4)
Name Description	BUD site selection

Chromosomal Location	ChrX:598735 to 603078 | ORF Map | GBrowse

	View Computational GO annotations for BUD4
Molecular Function
Manually curated	GTP binding (IDA, IMP)
Biological Process
Manually curated	axial cellular bud site selection (IMP) protein localization to bud neck (IMP)
Cellular Component
Manually curated	cellular bud neck contractile ring (IDA)
High-throughput	cellular bud neck (IDA)

Classical genetics
null	axial budding pattern: decreased bipolar budding pattern: increased cytokinesis: delayed Axl1p accumulation: abnormal Bud3p accumulation: abnormal Axl2p accumulation: abnormal GFP-Cdc12p distribution: abnormal
reduction of function	axial budding pattern: decreased bipolar budding pattern: increased
unspecified	axial budding pattern: decreased liquid culture appearance: abnormal
Large-scale survey
null	bud morphology: abnormal competitive fitness: decreased resistance to hydrogen chloride: increased viable
overexpression	vegetative growth: decreased rate
unspecified	resistance to Calcofluor White: increased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	69 total interaction(s) for 53 unique genes/features.
Physical Interactions	Affinity Capture-MS: 15 Affinity Capture-RNA: 3 Affinity Capture-Western: 9 Biochemical Activity: 9 Reconstituted Complex: 5 Two-hybrid: 2
Genetic Interactions	Dosage Lethality: 1 Negative Genetic: 6 Phenotypic Enhancement: 7 Phenotypic Suppression: 3 Positive Genetic: 3 Synthetic Growth Defect: 2 Synthetic Lethality: 1 Synthetic Rescue: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrX:598735 to 603078 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 2008-06-04
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..4344 598735..603078 2011-02-03 2008-06-04
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003852