BPH1/YCR032W Summary

BPH1 BASIC INFORMATION

Standard Name	BPH1
Systematic Name	YCR032W
Feature Type	ORF, Verified
Description	PProtein homologous to human Chediak-Higashi syndrome and murine Beige proteins, which are implicated in disease syndromes due to defective lysosomal trafficking; mutant phenotype and genetic interactions suggest a role in protein sorting (1, 2)
Name Description	Beige Protein Homolog 1

GO Annotations	All BPH1 GO evidence and references
	View Computational GO annotations for BPH1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	fungal-type cell wall organization (IMP) intracellular protein transport (IMP) response to pH (IMP)
Cellular Component
Manually curated	peripheral to membrane of membrane fraction (IDA) soluble fraction (IDA)
High-throughput	mitochondrion (IDA)

Mutant Phenotype	All BPH1 Phenotype details and references
Large-scale survey
null	sporulation: decreased viable

Interactions	BPH1 All interactions details and references
	9 total interaction(s) for 9 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2
Genetic Interactions	Dosage Rescue: 6 Phenotypic Enhancement: 1

Sequence Information

ChrIII:179516 to 186019 | |

This feature contains embedded feature(s): YCRX03C

Last Update

Coordinates: 2006-01-12 | Sequence: 2000-09-13

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..6504	179516..186019	2006-01-12	2000-09-13

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000628

BPH1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for BPH1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for BPH1]

1)	Perou CM, et al. (1996) Complementation of the beige mutation in cultured cells by episomally replicating murine yeast artificial chromosomes. Proc Natl Acad Sci U S A 93(12):5905-9
2)	Shiflett SL, et al. (2004) Bph1p, the Saccharomyces cerevisiae homologue of CHS1/beige, functions in cell wall formation and protein sorting. Traffic 5(9):700-10

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