AXL1/YPR122W Summary Help

AXL1 BASIC INFORMATION

Standard Name AXL1 1
Systematic Name YPR122W
Alias FUS5 2 , STE22 3
Feature Type ORF, Verified
Description Haploid specific endoprotease that performs one of two N-terminal cleavages during maturation of a-factor mating pheromone; required for axial budding pattern of haploid cells (1, 3, 4, 5)
Name Description AXiaL budding 1
GO Annotations All AXL1 GO evidence and references
    View Computational GO annotations for AXL1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All AXL1 Phenotype details and references
Classical genetics
null
reduction of function
Large-scale survey
null
Interactions AXL1 All interactions details and references
9 total interaction(s) for 9 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-Western: 2
Genetic Interactions
  • Dosage Rescue: 1
  • Phenotypic Enhancement: 2
  • Phenotypic Suppression: 1
  • Synthetic Rescue: 2
Sequence Information
ChrXVI:782041 to 785667 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-07-21 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..3627 782041..785667 2004-07-21 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000006326

AXL1 RESOURCES

Click on map for expanded view
SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for AXL1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for AXL1]

1) Fujita A, et al.  (1994) A yeast gene necessary for bud-site selection encodes a protein similar to insulin-degrading enzymes. Nature 372(6506):567-70
2) Kurihara LJ, et al.  (1994) Nuclear congression and membrane fusion: two distinct events in the yeast karyogamy pathway. J Cell Biol 126(4):911-23
3) Adames N, et al.  (1995) Role of yeast insulin-degrading enzyme homologs in propheromone processing and bud site selection. Science 270(5235):464-7
4) Chen P, et al.  (1997) Biogenesis of the Saccharomyces cerevisiae mating pheromone a-factor. J Cell Biol 136(2):251-69
5) Lord M, et al.  (2002) Subcellular localization of Axl1, the cell type-specific regulator of polarity. Curr Biol 12(15):1347-52