Standard Name	ATR1
Systematic Name	YML116W
Alias	SNQ1
Feature Type	ORF, Verified
Description	Multidrug efflux pump of the major facilitator superfamily; required for resistance to aminotriazole and 4-nitroquinoline-N-oxide; ATR1 has a paralog, YMR279C, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress (1, 2, 3, 4)
Name Description	AminoTriazole Resistance 1

Chromosomal Location	ChrXIII:38196 to 39824 | ORF Map | GBrowse

	View Computational GO annotations for ATR1
Molecular Function
Manually curated	borate transmembrane transporter activity (IMP) drug transmembrane transporter activity (IMP)
Biological Process
Manually curated	borate transport (IMP) drug transmembrane transport (IMP)
Cellular Component
Manually curated	plasma membrane (IDA, IMP) vacuole (IDA)
High-throughput	integral to membrane (ISM)

Classical genetics
null	elemental boron accumulation: increased metal resistance: decreased resistance to coniferyl aldehyde: decreased resistance to boric acid: decreased
overexpression	resistance to boric acid: increased
Large-scale survey
null	competitive fitness: decreased Rad52-YFP distribution: increased resistance to 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	6 total interaction(s) for 6 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 2 Two-hybrid: 2
Genetic Interactions	Dosage Rescue: 1 Negative Genetic: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:38196 to 39824 | ORF Map | GBrowse
Last Update	Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1629 38196..39824 1996-07-31 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB

Primary SGDID	S000004584