| Standard Name | ATO2 1 |
|---|---|
| Systematic Name | YNR002C |
| Alias | FUN34 2 |
| Feature Type | ORF, Verified |
| Description | Putative transmembrane protein involved in export of ammonia; ammonia is a starvation signal that promotes cell death in aging colonies; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family; homolog of Y. lipolytica Gpr1p; ATO2 has a paralog, ADY2, that arose from the whole genome duplication (1, 3, 4, 5, 6, 7) |
| Name Description | Ammonia (Ammonium) Transport Outward 1 |
| Chromosomal Location | |
|---|---|
| Note: this feature is encoded on the Crick strand. | |
Gene Ontology Annotations All ATO2 GO evidence and references
| View Computational GO annotations for ATO2 | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated | |
| High-throughput |
Mutant phenotypes All ATO2 Phenotype evidence and references
| Classical genetics | |
|---|---|
| unspecified | |
| Large-scale survey | |
| null |
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| Resources |
interactions All ATO2 Interaction evidence and references
| 11 total interaction(s) for 11 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All ATO2 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
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| Last Update | Coordinates: 2011-02-03 | Sequence: 1997-01-28 | ||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000005285 |
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References cited on this page View Complete Literature Guide for ATO2
| 1) | Palkova Z, et al. (2002) Ammonia pulses and metabolic oscillations guide yeast colony development. Mol Biol Cell 13(11):3901-14 |
| 2) | Lalo D, et al. (1993) Two yeast chromosomes are related by a fossil duplication of their centromeric regions. C R Acad Sci III 316(4):367-73 |
| 3) | Augstein A, et al. (2003) Characterization, localization and functional analysis of Gpr1p, a protein affecting sensitivity to acetic acid in the yeast Yarrowia lipolytica. Microbiology 149(Pt 3):589-600 |
| 4) | Vachova L, et al. (2004) Sok2p transcription factor is involved in adaptive program relevant for long term survival of Saccharomyces cerevisiae colonies. J Biol Chem 279(36):37973-81 |
| 5) | Vachova L and Palkova Z (2005) Physiological regulation of yeast cell death in multicellular colonies is triggered by ammonia. J Cell Biol 169(5):711-7 |
| 6) | Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 |
| 7) | Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 |





