ATM1/YMR301C Summary

ATM1 BASIC INFORMATION

Standard Name	ATM1 1
Systematic Name	YMR301C
Feature Type	ORF, Verified
Description	Mitochondrial inner membrane ATP-binding cassette (ABC) transporter, exports mitochondrially synthesized precursors of iron-sulfur (Fe/S) clusters to the cytosol (1, 2, 3)
Name Description	ABC Transporter, Mitochondrial 1

GO Annotations	All ATM1 GO evidence and references
	View Computational GO annotations for ATM1
Molecular Function
Manually curated	ATPase activity (IDA) ATPase activity, coupled to transmembrane movement of substances (IMP, ISS)
Biological Process
Manually curated	cellular iron ion homeostasis (IMP)
Cellular Component
Manually curated	mitochondrial inner membrane (IDA)
High-throughput	mitochondrion (IDA)

Mutant Phenotype	All ATM1 Phenotype details and references
Classical genetics
null	glutathione disulfide accumulation: increased iron accumulation: increased
Large-scale survey
null	inviable resistance to tenovin-6: decreased vegetative growth: decreased

Interactions	ATM1 All interactions details and references
	5 total interaction(s) for 5 unique genes/features.
Physical Interactions	Affinity Capture-Western: 1
Genetic Interactions	Dosage Lethality: 2 Dosage Rescue: 1 Synthetic Lethality: 1

Sequence Information

ChrXIII:869626 to 867554 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-02-27 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..2073	869626..867554	2004-02-27	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| TCDB \| UniProtKB

Primary SGDID	S000004916

ATM1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for ATM1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ATM1]

1)	Leighton J and Schatz G (1995) An ABC transporter in the mitochondrial inner membrane is required for normal growth of yeast. EMBO J 14(1):188-95
2)	Kispal G, et al. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J 18(14):3981-9
3)	Kispal G, et al. (1997) The ABC transporter Atm1p is required for mitochondrial iron homeostasis. FEBS Lett 418(3):346-50

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